Current status of clinical islet transplantation

Table 1 Summary of current open clinical trials with interventions in islet transplantation (Adapted from Clinical Trials.gov)

Trial ID	Description	Institution
NCT01653899	Caspase Inhibition in Islet Transplantation	University of Alberta
NCT00468117	Efficacy of Islet After Kidney Transplantation	National Institute of Allergy and Infectious Diseases
NCT01705899	Islet Allotransplantation in Type 1 Diabetes	Ohio State University
NCT01652911	A Phase I/II Study of the Safety and Efficacy of Sernova's Cell PouchTM for Therapeutic Islet Transplantation	University of Alberta
NCT00784966	Islet After Kidney Transplant for Type 1 Diabetes	Virginia Commonwealth University
NCT00790257	Safety and Efficacy Study of Encapsulated Human Islets Allotransplantation to Treat Type 1 Diabetes	Cliniques universitaires Saint-Luc-Université Catholique de Louvain
NCT00853944	Effect of Sitagliptin on Graft Function Following Islet Transplantation	University of British Columbia
NCT00249652	Transplant and Addiction Project 1	National Institute on Drug Abuse
NCT00530686	Pancreatic Islet Cell Transplantation - A Novel Approach to Improve Islet Quality and Engraftment	Baylor Research Institute
NCT01123187	Islet Cell Transplantation in Patients With Type 1 Diabetes With Previous Kidney Transplantation	University Hospital, Lille
NCT01817959	Study to Assess Efficacy and Safety of Reparixin in Pancreatic Islet Transplantation	Dompé s.p.a.
NCT00679042	Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago Protocol	University of Illinois
NCT00453817	Islet of Langerhans Graft Monitoring by Magnetic Resonance Imaging	University Hospital, Geneva
NCT00853424	A Comparison of Islet Cell Transplantation With Medical Therapy for the Treatment of Diabetic Eye Disease	University of British Columbia
NCT00789308	Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation	National Institute of Allergy and Infectious Diseases
NCT01148680	Trial Comparing Metabolic Efficiency of Islet Graft to Intensive Insulin Therapy for Type 1 Diabetes’s Treatment	University Hospital, Grenoble
NCT01241864	Islet Transplantation in Type 1 Diabetic Kidney Allograft	University of Chicago
NCT01722682	Bone Marrow vs Liver as Site for Islet Transplantation	Ospedale San Raffaele
NCT01630850	Islet Transplantation in Patients With\Brittle\“Type 1 Diabetes”	University of Chicago
NCT01186562	Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant	University of Minnesota
NCT01285934	A Trial of High Dose Immunosuppression and Autologous Hematopoietic Stem Cell Support Versus Intensive Insulin Therapy in Adults With Early Onset T1DM	University of Sao Paulo General Hospital
NCT00646724	Cotransplantation of Islet and Mesenchymal Stem Cell in Type 1 Diabetic Patients	Fuzhou General Hospital
NCT01379729	Bet Cell Therapy in Diabetes Type 1	AZ-VUB
NCT01341899	Efficacy and Safety Study of Autologous Hematopoietic Stem Cell Transplantation to Treat New Onset Type 1 Diabetes	The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT01736228	Open-label Investigation of the Safety and Efficacy of DIABECELL in Patients With T1DM	Living Cell Technologies
NCT01346098	Islet Autotransplantation in Patients at Very High-risk Pancreatic Anastomosis	Ospedale San Raffaele
NCT00989547	Cord Blood Infusion for T1DM	Technische Universität München
NCT00807651	Autologous Hematopoietic Stem Cell Transplantation for Early Onset Type 1 Diabetes	Shanghai Jiao Tong University School of Medicine
NCT01042301	Profiling of Original Cellular and Humoral Biomarkers of Type 1 Diabetes	Nantes University Hospital
NCT01350219	Stem Cell Educator Therapy in Type 1 Diabetes	Tianhe Stem Cell Biotechnologies Inc.
NCT00014911	Immunosuppressive Medications for Participants in ITN005CT	National Institute of Allergy and Infectious Diseases