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Letter to the Editor
Copyright ©The Author(s) 2025.
World J Transplant. Dec 18, 2025; 15(4): 108372
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.108372
Table 1 Comparison of veno-arterial and veno-venous extracorporeal membrane oxygenation
Feature
Veno-arterial ECMO
Veno-venous ECMO
Cardiac supportSupports systemic circulationDoes not support systemic circulation
CannulationArterial and venousVenous only
Pulmonary circulationDecreases pulmonary artery pressuresMaintains pulmonary circulation
Perfusion ratesRequires lower ratesRequires higher rates
Partial pressure of oxygen in arterial bloodHigher achievableLower achievable
ECMO circuit configurationConnected in parallel to heart and lungsConnected in series to heart and lungs