Physiology and health assessment, risk balance, and model for end-stage liver disease scores: Postoperative outcome of liver transplantation

Table 1 Demographic and clinical characteristics of liver transplant patients in the immediate postoperative period, n (%)/mean ± SD/ median (P25-P75)

Variables	n = 283
Recipient age (years)	58.1 ± 9.4
Recipient gender
Female	94 (33.2)
Male	189 (66.8)
Donor age (years)	41.6 ± 16.7
Donor gender
Female	90 (31.8)
Male	193 (68.2)
Cold ischemia time (hours)	3.1 (2.4-3.8)
ICU time (days)	5 (3-7)
Transplant day MELD	24.2 ± 5.3
APACHE IV	59.6 ± 23.4
APACHE IV probability of death	2.57 (1.51-4.78)
BAR score	10.7 ± 3.2
Death in 28 days	27 (9.5)
Death in 90 days	9/256 (3.5)

ICU: Intensive care unit; APACHE: Acute Physiology and Chronic Health Evaluation IV; BAR: Balance of risk; MELD: Model for end-stage liver.

Table 2 Probability of survival over time

	1 month	3 months	6 months	1 year	2 years	3 years	4 years	5 years
Survival rate (%)	90.1	87.6	85.9	82.5	79.6	78.2	78.2	78.2

Table 3 Areas under the curve for death at 28 and 90 days

Variables	Death in 28 days						Death in 90 days
	AUC	95%CI	P value	Cutoff point	Sensitivity	Specificity	AUC	95%CI	P value	Cutoff point	Sensitivity	Specificity
APACHE IV	0.85	0.76-0.94	< 0.001	71.50	77.80%	83.20%	0.80	0.71-0.90	< 0.001	64.50	77.80%	72.10%
BAR score	0.70	0.58-0.81	0.001	10.50	66.70%	55.90%	0.66	0.55-0.77	0.004	10.50	61.10%	55.90%
MELD	0.66	0.55-0.78	0.006	24	77.80%	35.20%	0.62	0.51-0.72	0.026	24	75.00%	35.20%

APACHE: Acute Physiology and Chronic Health Evaluation IV; BAR: Balance of risk; MELD: Model for end-stage liver.

Table 4 Comparison between variables and deaths at 28 days, 90 days, and overall death, mean ± SD/ median (P25 – P75)

Variables	Death in 28 days			Death in 90 days			Death
	Yes	No	P value	Yes	No	P value	Yes	No	P value
Recipient's age	59.2 ± 12.1	58.0 ± 9.1	0.604	62.4 ± 7.0	57.8 ± 9.2	0.135	59.3 ± 9.3	57.8 ± 9.5	0.275
ICU stay time	5 (3-8)	5 (3-7)	0.603	5 (4.5-18)	5 (3-7)	0.114	5 (3-10)	5 (3-7)	0.130
Cold ischemia time	3.3 (2.4-4.2)	3.1 (2.4-3.8)	0.634	2.9 (1.6-3.4)	3.1 (2.4-3.8)	0.208	3.3 (2.5-3.8)	3.1 (2.4-3.8)	0.571
APACHE IV points	92.0 ± 32.1	56.1 ± 19.4	< 0.001	86.1 ± 32.5	55.7 ± 18.9	< 0.001	76.5 ± 30.4	55.2 ± 19.0	< 0.001
APACHE IV prob death	13.4 (4.6-26.9)	2.4 (1.4-4.1)	< 0.001	11.6 (3.6-25.3)	2.3 (1.4-3.9)	< 0.001	4.9 (2.2-18.7)	2.3 (1.4-3.9)	< 0.001
BAR	13.2 ± 4.1	10.5 ± 2.9	0.002	12.7 ± 4.1	10.5 ± 2.9	0.003	11.8 ± 3.8	10.5 ± 2.9	0.016
MELD	28.3 ± 8.1	23.7 ± 4.7	0.008	27.1 ± 7.7	23.7 ± 4.7	0.016	26.1 ± 6.7	23.7 ± 4.8	0.013

ICU: Intensive care unit; APACHE: Acute Physiology and Chronic Health Evaluation IV; BAR: Balance of risk; MELD: Model for end-stage liver.