Retrospective Study
Copyright ©The Author(s) 2024.
World J Transplant. Sep 18, 2024; 14(3): 92981
Published online Sep 18, 2024. doi: 10.5500/wjt.v14.i3.92981
Table 1 Statistical analysis of pre-and post-Medicaid expansion in adult kidney transplant recipients for the state of Oklahoma
Variables
Before medicaid expansion (n = 2758)
After medicaid expansion (n = 141)
P value
Recipient age, median (IQR)53.0 (21.0)51.0 (22.0)0.3999c
Gender
    Female1089 (39.5) 56 (39.7)0.9563
    Male1669 (60.5) 85 (60.3)
Recipient BMI, Median (IQR)27.8 (7.6)28.4 (8.0)0.1549c
Race
    White1708 (61.9) 75 (53.2)< 0.0001
    Black531 (19.3) 22 (15.6)
    Amer Ind/Alaska Native/Pacific Islander215 (7.8) 13 (9.2)
    Hispanic204 (7.4) 18 (12.8)
    Asian68 (2.5) 12 (8.5)
    Multiracial32 (1.2) 1 (0.7)
Citizenship at transplant
    United States citizen2696 (97.8) 133 (94.3) 0.0188a
    Non-United States citizen62 (2.3) 8 (5.7)
ESRD diagnosis
    Other1423 (51.8) 85 (60.3) 0.0646
    Diabetes778 (28.3) 26 (18.4)
    Hypertension546 (19.9) 30 (21.3)
History of a previous kidney transplant306 (11.1) 14 (9.9) 0.6665
Recipient pretransplant dialysis2303 (83.9) 110 (78.0) 0.0673
Initial calculated EPTS
< 20%2086 (75.6) 61 (43.3) < 0.0001
≥ 20%672 (24.4) 80 (56.7)
PRA, median (IQR)0.0 (27.0)0.0 (37.0)0.3133c
Recipient functional status at transplant
Able to carry on normal activity and to work. No special care needed2158 (80.6) 11 (80.9) 0.5848
Unable to work; able to live at home and care for most personal needs; varying amount of assistance needed499 (18.6) 27 (19.2)
Unable to care for self; requires equivalent of institutional or hospital care; diseases may be progressing rapidly20 (0.8) 0 (0.0)
Recipient functional status-most recent at follow-up
    Able to carry on normal activity and to work. No special care needed1025 (80.8)116 (82.3) 0.1781
    Unable to work; able to live at home and care for most personal needs; varying amount of assistance needed197 (15.5) 24 (17.0)
    Unable to care for self; requires equivalent of institutional or hospital care; diseases may be progressing rapidly46 (3.6) 1 (0.7)
Total days on waiting list/including inactive time, median (IQR) 410.0 (683.0)253.0 (621.0) 0.0011c
Donor type
    Deceased donor2098 (76.1) 111 (78.7) 0.4705
    Living donor 660 (23.9) 30 (21.3)
DCD donor469 (22.4) 33 (29.7) 0.0708
Deceased donor kidney biopsy 681 (32.5) 46 (41.4) 0.0497
Donor kidney glomerulosclerosis, %
    ≤ 20 709 (98.6) 52 (100.0) 1.0000a
    > 20 10 (1.4) 0 (0.0)
HLA mismatch level
    0199 (7.2) 9 (6.4) 0.0161
    170 (2.5) 1 (0.7)
    2203 (7.4) 7 (5.0)
    3439 (16.0) 21 (15.0)
    4678 (24.7) 54 (38.6)
    5800 (29.1) 31 (22.1)
    6362 (13.2) 17 (12.1)
Delayed graft function408 (14.8) 27 (19.2) 0.1578
KDPI
    Low < 20% 648 (31.0) 40 (36.0) 0.4063
    Moderate 20%-85% 1375 (65.7) 69 (62.2)
    High > 85%69 (3.3) 2 (1.8)
KDPI, median (IQR)34.0 (40.0) 34.0 (50.0)0.9930c
Share type
Local 2437 (88.4) 68 (48.2) < 0.0001
Regional 101 (3.7) 24 (17.0)
National 220 (8.0) 49 (34.8)
Kidney cold ischemic time (hours), median (IQR)12.0 (12.5) 16.0 (12.9) < 0.0001c
Rejection within 6 months 176 (7.5) 9 (16.4)0.0344a
Post TX
Recipient primary insurance at transplant
Private insurance835 (30.3) 47 (33.3) 0.5142b
Public insurance1921 (69.7) 94 (66.7)
Other2 (0.1)0 (0.0)
Working for income 876 (34.7) 57 (42.2) 0.0752
Table 2 Post-expansion recipient functional status at transplant by different insurance types
Functional status at transplant
Private insurance (%)
Public insurance (%)
Other (%)
P value
Able to carry on normal activity and to work. No special care needed1083 (86.4)1184 (75.9)5 (100.0)0.0003b
Unable to work; able to live at home and care for most personal needs; varying amount of assistance needed168 (13.4)358 (23.0)0 (0.0)
Unable to care for self; requires equivalent of institutional or hospital care; diseases may be progressing rapidly2 (0.2)18 (1.2)0 (0.0)
Table 3 Post-Medicaid expansion recipients’ insurance types, n (%)
Insurance
White 1783 (61.6)
Black 553 (19.1)
AI/NH/PI
(0.08)
Hispanic
(0.08)
Asian
(0.03)
Multiracial (0.01)
P value
Private insurance 905 (50.8)181 (32.7)91 (39.9)80 (36.0)35 (43.8)7 (21.2)0.0003
Public insurance 874 (49.0)371(67.1)137 (60.1)142 (64.0)45 (56.3)26 (78.8)
Other4 (0.22)1 (0.18)0 (0.00)0 (0.00)0 (0.00)0 (0.00)
Table 4 Post-expansion recipient functional status at Transplant by different race, n (%)
Recipient functional status transplant
White 1783 (61.6)
Black 553 (19.1)
AI/NH/PI
(0.08)
Hispanic
(0.08)
Asian (0.03)
Multiracial
(0.01)
P value
Able to carry on normal activity and to work. No special care needed 1391 (80.5)435 (79.7)178 (81.3)178 (81.7)65 (85.5)25 (78.1)0.8401b
Unable to work; able to live at home and care for most personal needs; varying amount of assistance needed 322 (18.7)108 (19.8)40 (18.3)39 (17.9)11 (14.5)6 (18.8)
Unable to care for self; requires equivalent of institutional or hospital care; diseases may be progressing rapidly 14 (0.81)3 (0.55)1 (0.46)1 (0.46)0 (0.00)1 (3.1)
Table 5 Cox proportional hazards model for a hazard ratio of variables for 1-year patient survival
Variables
aHR (95%CI)
P value
Age 1.04 (1.03, 1.05)< 0.0001
Sex
    FemaleReference
    Male 1.19 (1.01, 1.40)0.0426
Race
    White Reference
    Black 0.98 (0.87, 1.20)0.8699
    Amer Ind/Alaska Native/Pacific Islander1.52 (1.18, 1.97)0.0014
    Hispanic0.82 (0.58, 1.17)0.2748
    Asian0.73 (0.40, 1.33)0.3056
    Multiracial1.05 (0.34, 3.32)0.9289
Insurance
    Private insurance Reference
    Public insurance1.54 (1.25, 1.88)< 0.0001
Recipient functional status at transplant
    Able to carry on normal activity and to work. No special care needed Reference
    Unable to work; able to live at home and care for most personal needs; varying amount of assistance needed 1.53 (1.27, 1.84)< 0.0001
    Unable to care for self; requires equivalent of institutional or hospital care; diseases may be progressing rapidly 2.13 (1.09, 4.20)0.0281
Medicaid expansion
    Before medicaid expansionReference
    After medicaid expansion 1.07 (0.26, 4.41)0.9290