Histopathological characteristics and causes of kidney graft failure in the current era of immunosuppression

Figure 1 Study design: Death censored graft failure from 2006-2016 with allograft biopsy within one year prior to the graft failure.

Figure 2 All histological findings on the biopsy. Interstitial fibrosis and tubular atrophy, acute rejection, and transplant glomerulopathy were the common histological findings in the failing graft.

Figure 3 Overall causes of graft failure. Acute rejection is the most common cause of graft failure based on the primary biopsy diagnosis.

Figure 4 Causes of graft failure since time of transplant. IFTA: Interstitial fibrosis and tubular atrophy.

Figure 5 Transplant glomerulopathy is the predominant cause of graft failure after the 6^th year. P < 0.05 compared to > 6 yr between acute rejection, transplant glomerulopathy and other.