Preconditioning with sufentanil confers protective effects in transplantation by attenuating hepatic ischemia-reperfusion injury

doi:10.5500/wjt.v16.i2.120865

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Transplant. Jun 18, 2026; 16(2): 120865
Published online Jun 18, 2026. doi: 10.5500/wjt.v16.i2.120865

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Figure 1 Schematic mechanisms of hepatic ischemia-reperfusion injury. NO: Nitric oxide; ATP: Adenosine triphosphate; Ca: Calcium; ROS: Reactive oxygen species; pH: Potential of hydrogen; TNF: Tumor necrosis factor; IL: Interleukin; NF-κB: Nuclear factor kappa-B.

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Figure 2 Simplified mechanisms of ferroptosis. ROS: Reactive oxygen species; GSH: Glutathione; GPX4: Glutathione peroxidase 4; CoQ10: Coenzyme Q10.

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Figure 3 Structural comparison of sufentanil, fentanyl, and morphine.

Citation: Mouratidou C, Pavlidis ET, Katsanos G, Kofinas A, Marneri AG, Stavrati KE, Tsoulfas G, Pavlidis TE. Preconditioning with sufentanil confers protective effects in transplantation by attenuating hepatic ischemia-reperfusion injury. World J Transplant 2026; 16(2): 120865
URL: https://www.wjgnet.com/2220-3230/full/v16/i2/120865.htm
DOI: https://dx.doi.org/10.5500/wjt.v16.i2.120865

Mouratidou C, Pavlidis ET, Katsanos G, Kofinas A, Marneri AG, Stavrati KE, Tsoulfas G, Pavlidis TE. Preconditioning with sufentanil confers protective effects in transplantation by attenuating hepatic ischemia-reperfusion injury. World J Transplant 2026; 16(2): 120865 [DOI: 10.5500/wjt.v16.i2.120865]

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