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©The Author(s) 2025.
World J Exp Med. Mar 20, 2025; 15(1): 101771
Published online Mar 20, 2025. doi: 10.5493/wjem.v15.i1.101771
Published online Mar 20, 2025. doi: 10.5493/wjem.v15.i1.101771
Figure 1
Protonated and deprotonated forms of ursodeoxycholic acid, tauroursodeoxycholic acid, and glycoursodeoxycholic acid.
Figure 2
Formulation of the protonated and deprotonated form of obeticholic acid.
Figure 3
Formulas of norursodeoxycholic acid and its glucuronide in protonated and deprotonated forms.
Figure 4 Cholehepatic bypass and metabolism of norursodeoxycholic acid glucuronide.
norUDCA: Norursodeoxycholic acid glucuronide; MRP: Multidrug-resistance protein.
- Citation: Reshetnyak VI, Maev IV. Bile acid therapy for primary biliary cholangitis: Pathogenetic validation. World J Exp Med 2025; 15(1): 101771
- URL: https://www.wjgnet.com/2220-315x/full/v15/i1/101771.htm
- DOI: https://dx.doi.org/10.5493/wjem.v15.i1.101771