Mood disorders: A potential link between ghrelin and leptin on human body?

Table 1 Leptin in patients with mood disorders according study’s since 2004

Ref.	Findings
Westling et al[51]	Low CSF leptin in MDD women
Atmaca et al[52]	Low in OCD + D
Esel et al[57]	High in women but not in men
Gecici et al[54]	High in patients with atypical depressive disorder but not with non-atypical
Jow et al[50]	Low
Emul et al[53]	No difference
Pasco et al[47]	High in females non-smokers
Jimenez et al[46]	High in patients with post-stroke depression
Hafner et al[56]	High in men with social isolation and depressed
Lawson et al[45]	Low
Hafner et al[55]	High in normal-weight women
During antidepressant therapy
Himmerich et al[42]	High after successful treatment

CSF: Cerebrospinal fluid; MDD: Major depressive disorder; OCD + D: Obsessive compulsive disorder + depression.

Table 2 Ghrelin in patients with mood disorders according study’s since 2007

Ref.	Findings
Rouach et al[80]	High in patients with binge-eating disorders
Schanze et al[62]	No difference
Kluge et al[78]	No difference
Barim et al[68]	Low
Matsuo et al[79]	No difference
Ishitobi et al[84]	High in non-responders with MDD
Ozsoy et al[81]	High
Treatment and ghrelin levels
Schmid et al[83]	Decrease with mirtazapine

MDD: Major depressive disorder.