Copyright
©The Author(s) 2017.
World J Crit Care Med. Feb 4, 2017; 6(1): 56-64
Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.56
Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.56
Table 1 Admission characteristics and outcome data
All | Before | After | P-value (before vs after) | |
Admission characteristics | ||||
n of pt | 480 | 231 | 249 | |
Male gender, n (%) | 298 (62.1) | 151 (65.4) | 147 (59.0) | 0.159 |
Surgical profile, n (%) | 256 (53.3) | 120 (51.9) | 136 (54.6) | 0.311 |
Abdominal surgery, n (%) | 141 (29.4) | 72 (31.2) | 69 (27.7) | 0.232 |
Age, mean (range) | 61.7 (18-96) | 61.5 (18-96) | 62.0 (20-93) | 0.684 |
BMI | 27.8 (24.3-31.6) | 27.7 (24.5-31.5) | 27.8 (24.3-32.0) | 0.791 |
APACHE II, points | 16 (11.0-22.0) | 16 (11.0-21.0) | 16 (12.0-22.0) | 0.948 |
SOFA, points | 8 (6.0-10.0) | 8 (6.0-10.0) | 8 (7.0-10.0) | 0.504 |
Vasopressor/inotrope, n (%) | 407 (84.8) | 195 (84.4) | 212 (85.1) | 0.462 |
Mechanical ventilation, n (%) | 431 (89.8) | 215 (93.1) | 216 (86.7) | 0.021 |
Outcomes | ||||
ICU stay (d) | 13 (9-21) | 13 (9-22) | 13 (8-21) | 0.978 |
Mechanical ventilation (d) | 10 (6-17) | 9 (6-18) | 10 (6-17) | 0.796 |
Ventilator pneumonia, n (%) | 16 (3.3) | 7 (3.0) | 9 (3.6) | 0.461 |
Urinary tract infection, n (%) | 31 (6.5) | 16 (6.9) | 15 (6.0) | 0.582 |
Bloodstream infection, n (%) | 16 (3.3) | 6 (2.6) | 10 (4.0) | 0.404 |
Cl difficile colitis, n (%) | 14 (2.9) | 6 (2.6) | 8 (3.2) | 0.450 |
ICU mortality | 51 (10.6) | 28 (12.1) | 23 (9.2) | 0.190 |
30-d mortality | 121 (25.2) | 64 (27.7) | 52 (22.9) | 0.134 |
60-d mortality | 136 (28.3) | 73 (31.6) | 63 (25.3) | 0.076 |
90-d mortality | 157 (32.7) | 86 (37.2) | 71 (28.5) | 0.026 |
120-d mortality | 164 (34.2) | 89 (38.5) | 75 (30.1) | 0.033 |
Table 2 Daily enteral caloric intake
Daily enteral caloric intake | Before | After | P-value |
Median (IQR), kcal | Median (IQR), kcal | ||
Day 1 | 0 (0-100) | 0 (0-0) | 0.016 |
Day 2 | 0 (0-480) | 100 (0-480) | 0.409 |
Day 3 | 160 (0-700) | 370 (0-767) | 0.031 |
Day 4 | 340 (0-800) | 500 (10-960) | 0.003 |
Day 5 | 400 (0-1000) | 580 (176-1100) | 0.142 |
Day 6 | 500 (53-1000) | 695 (240-1138) | 0.003 |
Day 7 | 500 (108-1000) | 720 (200-1155) | 0.018 |
Table 3 Seven-day cumulative enteral and parenteral caloric intake
Cumulative caloric intake | All | Before | After | P-value |
Median (IQR), kcal | Median (IQR), kcal | Median (IQR), kcal | (before vs after) | |
Cumulative EN calories day 7 | 2870 (803-5163) | 2300 (380-5030) | 3210 (1280-5215) | 0.049 |
Cumulative PN calories day 7 | 3100 (1338-5225) | 3977 (1775-6646) | 2600 (825-4287) | < 0.001 |
Cumulative total calories day 7 | 6531 (5035-8140) | 7030 (5667-8970) | 6000 (4715-7498) | < 0.001 |
Table 4 Regression analysis with day of admission variables predicting insufficient enteral feeding by day 4 and day 7
Variables predicting insufficient EN | Day 4 | Day 7 | ||
OR (95%CI) | P-value | OR (95%CI) | P-value | |
Before group | 4.02 (1.55-10.40) | 0.004 | 2.09 (1.35-3.22) | 0.001 |
Abdominal surgery | 3.97 (1.26-12.46) | 0.018 | 3.09 (1.82-5.27) | < 0.001 |
Sum of GI symptoms | 6.01 (2.55-14.14) | < 0.001 | 2.35 (1.60-3.44) | < 0.001 |
IAH | 4.20 (1.32-13.34) | 0.015 | - | - |
Nagelkerke R Square | 0.349 | 0.19 |
- Citation: Padar M, Uusvel G, Starkopf L, Starkopf J, Reintam Blaser A. Implementation of enteral feeding protocol in an intensive care unit: Before-and-after study. World J Crit Care Med 2017; 6(1): 56-64
- URL: https://www.wjgnet.com/2220-3141/full/v6/i1/56.htm
- DOI: https://dx.doi.org/10.5492/wjccm.v6.i1.56