Association of early interleukin-6 level with injury severity and mortality in trauma patients: Systematic review and meta-analysis

Figure 1  Flow chart of the study selection process.

Figure 2 Forest plot. A: Using the Pearson correlation coefficient to assess the correlation between interleukin (IL)-6 and injury severity score (ISS); B: Using the Spearman rank correlation coefficient to assess the correlation between IL-6 and ISS.

Figure 3 Funnel plot. A: For Pearson’s coefficient (Egger’s P-value = 0.007); B: For Spearman’s rank coefficient (Egger’s P-value = 0.91).

Figure 4  Forest plot of the mean difference of interleukin-6 between survivors and non-survivors on arrival.