Future of neurocritical care: Integrating neurophysics, multimodal monitoring, and machine learning

Figure 1 Lassen’s cerebral autoregulatory curve. Cerebral blood flow is normally reported to remain constant over a large mean arterial pressure range of 50-150 mmHg. This range is significantly shifted or narrower in patients with acute brain injury. The ischemic critical perfusion threshold is defined at 30 mL/100 g/min. This figure was generated using BioRender (Agreement No: SE269MFWGB).

Figure 2 General overview of the various invasive and noninvasive neuromonitoring tools, indications, methodology, and physiological basis in the treatment of neurocritical patients and acute brain injury. EEG: Electroencephalography; ICP_wf: Intracranial pressure wave-form. This figure was generated using BioRender (Agreement No: SE269MFWGB).