Diuretic combinations in critically ill patients with respiratory failure: A systematic review and meta-analysis

Figure 1 Flow chart of included studies.

Figure 2 Forest plot. A: Daily fluid balance; B: Urine output. Comparing loop diuretic in monotherapy to three combinations of diuretics (mineralocorticoid antagonist, thiazides and carbonic anhydrase inhibitor). Mean difference and 95% confidence intervals are shown for each study and the pooled analysis using a random effects model and the Mantel-Haenszel method. Mean difference > 0 means that urine output is higher in the group receiving the combination of diuretics.