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Observational Study
Copyright: ©Author(s) 2026.
World J Clin Pediatr. Dec 9, 2026; 15(4): 124664
Published online Dec 9, 2026. doi: 10.5409/wjcp.124664
Table 1 Demographic and anthropometric characteristics of the cohort, n (%)

Total cohort, n = 70
Normal weight, n = 26
Obesity, n = 44
P value
Age (years)10.8 (3.3)10.9 (3.7)10.7 (3.0)0.61
Sex0.82
    Female35 (50)14 (54)21 (48)
    Male35 (50)12 (46)23 (52)
Weight (kg)60.6 (25.1)47.5 (23.8)68.4 (22.7)< 0.0011
Height (cm)148.7 (19.6)147.2 (24.3)149.6 (16.5)0.921
BMI (kg/m2)26.0 (6.5)20.1 (4.8)29.5 (4.5)< 0.0011
BMI (SDS)2.2 (1.8)0.2 (1.0)3.3 (0.9)< 0.0011
VFA92.5 (58.0)44.9 (40.1)119.1 (48.9)< 0.0011
Body fat percentage (%)33.0 (12.1)20.4 (9.7)40.0 (6.0)< 0.0011
Family history of DM0.0272
    No27 (43)13 (65)14 (33)
    Yes36 (57)7 (35)29 (67)
Paternal educational level0.0562
    No formal education or incomplete primary school2 (3.8)0 (0)2 (6.5)
    Primary or secondary33 (62)11 (50)22 (71)
    University degree18 (34)11 (50)7 (23)
Maternal educational level0.0062
    No formal education or incomplete primary school2 (3.4)0 (0)2 (6.2)
    Primary or secondary38 (66)13 (50)25 (78)
    University degree18 (31)13 (50)5 (16)
Table 2 Biochemical and metabolic profiles by study group, n (%)

Total cohort, n = 70
Normal weight, n = 26
Obesity, n = 44
P value1
Mean SBP (mmHg)118.4 (15.8)111.8 (12.3)122.1 (16.4)0.009
Mean DBP (mmHg)66.4 (7.7)64.3 (6.0)67.5 (8.3)0.14
SBP percentile74.7 (25.6)64.7 (26.7)80.2 (23.6)0.008
DBP percentile62.3 (20.9)57.2 (20.0)65.0 (21.1)0.10
SBP (SDS)1.2 (1.4)0.6 (1.1)1.5 (1.4)0.006
DBP (SDS)0.4 (0.7)0.2 (0.6)0.5 (0.7)0.10
TSH (μU/mL)2.4 (1.1)2.5 (0.9)2.3 (1.1)0.2
Total cholesterol (mg/dL)145.4 (34.2)153.4 (33.3)141.3 (34.4)0.3
HDL-C (mg/dL)46.7 (9.9)53.0 (9.4)43.8 (8.8)< 0.001
LDL-C (mg/dL)88.2 (25.8)90.2 (24.8)87.3 (26.4)0.7
Triglycerides (mg/dL)77.3 (43.2)74.3 (34.5)78.9 (47.3)0.8
Fasting glucose (mg/dL)88.0 (7.2)86.8 (7.5)88.6 (7.1)0.3
Fasting insulin (μU/dL)12.7 (9.0)9.7 (7.3)14.1 (9.4)0.035
HOMA-IR2.8 (2.0)2.1 (1.7)3.1 (2.1)0.024
HbA1c (%)5.3 (0.3)5.3 (0.3)5.3 (0.2)0.9
GOT (U/L)27.4 (12.0)30.9 (14.9)25.7 (10.1)0.2
GPT (U/L)22.2 (11.5)18.6 (7.5)24.0 (12.9)0.069
GGT (U/L)15.6 (11.1)13.2 (2.7)16.7 (13.2)0.5
Uric acid (mg/dL)5.3 (1.3)4.8 (1.4)5.5 (1.3)0.13
Cortisol10.5 (3.6)12.2 (3.0)10.2 (3.7)0.2
Table 3 Lifestyle exposure parameters (diet, physical activity, and electronic screen time) and sleep quality disturbances, n (%)

Total cohort, n = 70
Normal weight, n = 26
Obesity, n = 44
P value
KIDMED score categories0.0292
    Very low quality20 (28.6)5 (19.2)15 (34.1)
    Needs improvement40 (57.1)20 (77)20 (45.4)
    Optimal10 (14.3)1 (3.8)9 (20.5)
Physical activity level0.0212
    Low36 (51.4)8 (30.8)28 (63.6)
    Moderate16 (22.9)6 (23.1)10 (22.7)
    High14 (20)9 (34.6)5 (11.4)
    Vigorous3 (4.3)2 (7.7)1 (2.3)
    Very vigorous1 (1.4)1 (3.8)0 (0)
K-P total score4.9 (2.6)6.0 (2.3)4.0 (2.6)0.0041
Screen time hours (K-P)2.6 (1.5)2.1 (1.4)2.9 (1.5)0.0471
Sports hours (K-P)2.9 (3.4)4.1 (4.1)2.0 (2.3)0.0111
Mean sleep duration (hours)8.7 (1.3)9.1 (1.5)8.4 (1.0)0.0211
Presence of chronic sleep disturbances (> 1 year)0.0162
    No41 (75)22 (92)19 (61)
    Yes14 (25)2 (8.3)12 (39)


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