Quality of life in children with chronic pancreatitis: An overlooked challenge

Table 1 Comparison of different studies on quality of life in children with chronic pancreatitis

Ref.	Age group (years)	Number of patients	Questionnaire used	QOL findings	Anxiety and depression	Gender impact	Pain impact	Exocrine insufficiency	Endocrine insufficiency	Advanced disease	Calcific pancreatitis	Socio-economic status	Impact of treatment modality
Pohl et al[29], 2012, United States	2–18	38	PedsQL 4.0	Poor physical and psychosocial QOL	Not studied	Not studied	Not studied	Not studied	Not studied	Not studied	Not studied	Not studied	Not studied
Bellin et al[30], 2011, United States	5–18	19	SF-36	Poor physical and mental component score	Not studied	Not studied	Not studied	Not studied	Not studied	Not studied	Not studied	Not studied	Surgery: Improvement in QOL score 1-year post-surgery
Tham et al[31], 2022, Multicentre (United States, Canada, Israel, Australia)	6–18	368	CHQ-PF50	Physical QOL poor; psychosocial QOL normal	19.3%	No	Yes	No association	No association	Not studied	Not studied	Not studied	Not studied
Agrawal et al[15], 2024, India	8–18	120	PedsQL 4.0	Both physical and psychosocial QOL poor	1.6%	Female had poor psychosocial QOL	Yes	No association	No association	No association	No association	Poor socio-economic status associated with poor QOL	Not studied

QOL: Quality of life; PedsQL 4.0: Pediatric quality of life inventory core generic scale; SF: Short form questionnaire; CHQ-PF50: Child health questionnaire-parent form.