Interface between inborn errors of immunity and rheumatological disorders in children: A pediatrician’s conundrum

Figure 1 Rheumatological manifestations in patients with underlying inborn errors of immunity. IBD: Inflammatory bowel disease; MAS: Macrophage activation syndrome; HLH: Hemophagocytic lymphohistiocytosis.

Figure 2  Red flags that point towards inborn errors of immunity presenting with rheumatological manifestations.

Figure 3  Various inborn errors of immunity that can present with arthritis as one of the predominant manifestations.

Figure 4  Genes affecting central and peripheral tolerance resulting in polyautoimmunity.