Impact of glucocorticoid therapy on hypothalamic-pituitary-adrenal axis function in pediatric nephrotic syndrome: A narrative review

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Dec 9, 2025 (publication date) through Nov 3, 2025

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Pediatr. Dec 9, 2025; 14(4): 110374
Published online Dec 9, 2025. doi: 10.5409/wjcp.v14.i4.110374

Figure 1 Hypothalamic-pituitary-adrenal axis. CRH: Corticotropin-releasing hormone; ACTH: Adrenocorticotropic hormone.

Citation: Sarkar S, Abeyagunawardena AS, Sinha R. Impact of glucocorticoid therapy on hypothalamic-pituitary-adrenal axis function in pediatric nephrotic syndrome: A narrative review. World J Clin Pediatr 2025; 14(4): 110374
URL: https://www.wjgnet.com/2219-2808/full/v14/i4/110374.htm
DOI: https://dx.doi.org/10.5409/wjcp.v14.i4.110374