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World J Stomatol. Aug 20, 2013; 2(3): 35-39
Published online Aug 20, 2013. doi: 10.5321/wjs.v2.i3.35
Published online Aug 20, 2013. doi: 10.5321/wjs.v2.i3.35
Type of stem cells after birth | Dental stem cell properties | Signaling inputs for reparative dentin formation |
Stem cells permanently present in the adult tooth: Dental pulp stem cell Periodontal ligament stem cells Apical papilla stem cells Stem cells present in deciduous tooth: Exfoliated deciduous teeth stem cells Stem cells present during crown formation: Dental follicule stem cells | Self-renewal Ability to enter in mitosis in response to appropriate signals and to differentiate towards odonto/osteogenic cells Long-term survival and maintenance of reparative capacity Distinct subpopulations expressing markers of mesenchymal stem cells of the bone marrow (STRO-1, CD44, CD 106, 3G5, CD146, CD90, Sca-1…) | Tooth injury may promotes stem cell recruitment by: Local secreted factors: bioactive extracellular matrix molecules Ca2+ release Mechanical inputs: changes in matrix elasticity Diffusible signals emanating from stromal, inflammatory, circulating… cells |
- Citation: Dimitrova-Nakov S, Harichane Y, Goldberg M, Kellermann O. Dental stem cells: Progress and perspectives. World J Stomatol 2013; 2(3): 35-39
- URL: https://www.wjgnet.com/2218-6263/full/v2/i3/35.htm
- DOI: https://dx.doi.org/10.5321/wjs.v2.i3.35