Intravascular proliferating anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma

Figure 1 Autopsy was performed. Hematoxylin-eosin staining in lymph node revealed diffuse proliferation of tumor cells in low power field (A); High power field imaging showed infiltrated atypical small lymphocytes (B); Immunohistochemical staining revealed that the tumor cells expressed anaplastic lymphoma kinase (C). ALK: Anaplastic lymphoma kinase.

Figure 2 Anaplastic lymphoma kinase positive tumor cells were selectively proliferating in intra lumina of vessels in lung (A, C) and heart (B, D), respectively.