Gemcitabine cures metastatic hepatic carcinoma and bone metastasis

Figure 1 Diagnosis of pancreas adenocarcinoma. A: Multiple liver metastasis (arrow); B: Enlarged pancreas head (curved arrow); C: Focal stenosis over the distal portion of the pancreatic duct (arrow, apple-core like).

Figure 2 Liver aspiration. A: Liver tissue with tumor arranged in solid sheet on the left side of the picture (HE stain, x 200); B: High power view shows tumor cells with hyperchromatic nuclei and high nucleus-to-cytoplasm (N/C) ratio (HE stain, x 400). Two patches of necrosis are found in the lower and right upper part; C: Tumor cells in solid nest with hyperchromatic nuclei and high N/C ratio. The right side is normal liver tissue (HE stain, x 400); D: AE1/AE3 (IHC stain, x 400). Focal cytoplasmic positive reaction (white arrow).

Figure 3 Tumor shrinkage post-chemotherapy. A: Liver nodules disappeared; B: The pancreas head was atrophied (white arrow); C: No stenosis of the pancreatic duct was noted after chemotherapy.

Figure 4 Shrinkage of left lobe of the liver (A, black arrow) and pancreatic head (B, white arrow).