Copyright
©The Author(s) 2016.
World J Orthop. Jan 18, 2016; 7(1): 20-29
Published online Jan 18, 2016. doi: 10.5312/wjo.v7.i1.20
Published online Jan 18, 2016. doi: 10.5312/wjo.v7.i1.20
Table 1 Pathophysiological factors involved in cervical myelopathy
| Static factors |
| Spondylosis |
| Disc degeneration |
| Ossification of the posterior longitudinal ligament |
| Ossification of ligamentum flavum |
| Congenital stenosis |
| Other acquired congenital pathology, e.g., tumors, calcification |
| Dynamic factors |
| Changes in neck flexion/extension - narrow spinal canal |
| Biomolecular factors |
| Ischemic injury - compression of spinal cord vasculature |
| Glutamate - mediated excitotoxicity |
| Oligodendrocyte and neuronal apoptosis |
- Citation: Dolan RT, Butler JS, O’Byrne JM, Poynton AR. Mechanical and cellular processes driving cervical myelopathy. World J Orthop 2016; 7(1): 20-29
- URL: https://www.wjgnet.com/2218-5836/full/v7/i1/20.htm
- DOI: https://dx.doi.org/10.5312/wjo.v7.i1.20
