Effect of early surgery in high surgical risk geriatric patients with femoral neck fracture and taking antiplatelet agents

Table 1 Patients’ characteristic data

		ES group (n = 49)	DS group (n = 45)	P value
Age1, yr		80 ± 8	81 ± 8	0.67
Female gender		34 (69)	35 (78)	0.36
BMI1, kg/m2		22.6 ± 2.8	23.3 ± 4.4	0.40
Fracture right side		24 (49)	24 (53)	0.67
No. of comorbid diseases
	0-1	18 (37)	11 (24)	0.25
	2 or more	31 (63)	34 (76)
ASA physical status
	3	39 (80)	28 (62)	0.07
	4	10 (20)	17 (38)
Time to surgery1		1.6 ± 0.9	8.9 ± 3.6	< 0.01
Type of antiplatelet agents
	Aspirin alone	42 (86)	36 (80)	0.59
	Clopidogrel	7 (14)	9 (20)
Preinjury ambulation status
	Walk independently	42 (86)	36 (80)	0.67
	Walk with gait aid	7 (14)	8 (18)
	Wheel chair or bed ridden	0 (0)	1 (2)
Preoperative laboratory value1
	Hemoglobin, g/dL	12.0 ± 1.6	11.2 ± 1.2	< 0.01
	Platelet count, × 103/mm3	241 ± 85	284 ± 96	0.03
	Creatinine clearance, mg/dL	1.3 ± 1.1	1.7 ± 1.7	0.92
	Serum albumin, g/L	35.6 ± 4.4	34.9 ± 5.3	0.53
	aPTT, s	27.5 ± 3.6	26.6 ± 4.3	0.34
	PT, s	11.9 ± 1.1	12.4 ± 2.5	0.23
Regional anesthesia		31 (63)	31 (69)	0.66
Type of operation
	Cemented	26 (53)	37 (82)	< 0.01
	Cementless	23 (47)	8 (18)
Operative time1, min		98 ± 27	102 ± 34	0.48

¹Value presented as mean ± SD; value presented as no. of patients (percentage). BMI: Body mass index; ASA: American Society of Anesthesiologists; aPtt: Activated partial thromboplastin time; PT: Prothrombin time.

Table 2 Blood loss outcomes

Bleeding outcome	ES group(n = 49)	DS group(n = 45)	P value
Blood loss1, mL
Intraoperative blood loss	291 ± 136	315 ± 224	0.52
Drainage blood loss	201 ± 131	178 ± 91	0.33
Total apparent blood loss	492 ± 210	493 ± 229	0.97
Calculated blood loss	292 ± 222	303 ± 187	0.8
PRC transfusion1, UI	0.6 ± 0.9	0.7 ± 0.8	0.49

¹Value presented as mean ± SD.

Table 3 Postoperative mortality and morbidity

Postoperative outcome	ES group(n = 49)	DS group(n = 45)	P value
Mortality	0 (0)	2 (4)	0.23
Postoperative complications
Overall	12	28	0.02
Pneumonia	2	5
Urinary tract infection	7	11
Pressure sore	0	2
Cardiac	0	3
Thromboembolic complication	2	2
Delirium	1	5
ICU requirement	19 (39)	14 (31)	0.39
LOS1, d	7 ± 3	14 ± 9	< 0.0001
PLOS1	6.1 ± 3.4	7.4 ± 7.8	0.28
Readmission	1 (2)	6 (13)	0.052
One-year ambulation status	n = 49	n = 43
Walk independently	18 (37)	7 (16)	0.03
Walk with gait aid	30 (61)	33 (77)
Wheelchair	0 (0)	3 (7)

¹Value presented as mean ± SD; value presented as no. of patients (percentage). Value presented as no. of incidence. ICU: Intensive care unit; LOS: Length of hospital stay; PLOS: Postoperative length of hospital stay.