Donor’s site evaluation after restoration with autografts or synthetic plugs in rabbits

Table 1 Mean international cartilage repair society scores per category and standard deviation of all groups

	BGS group	OA group	Control group
Surface (0,3)	1.2 ± 1.55	1.5 ± 1.58	0.9 ± 1.45
Matrix (0-3)	1.6 ± 1.35	3	0.7 ± 0.67
Cell distribution (0-3)	0.7 ± 0.82	2	0.1 ± 0.32
Cell viability (0,1,3)	3	3	2.6 ± 0.84
Subchondral bone (0-3)	1.4 ± 0.84	2	0.9 ± 1.19
Cartilage mineralization (0,3)	1.2 ± 1.55	3	0.6 ± 1.26

The mean scores are presented in bolt letters, while the standard deviation in simple ones. BGS: Biosynthetic graft substitute. OA: Osteochondral autograft.

Table 2 The presence of collagen type II is verified or not with the antibodies for collagen type II

	Presence of collagen II		Presence of collagen II		Presence of collagen II
Α1	Yes	Β1	Yes	C1	No
Α2	No	Β2	Yes	C2	No
Α3	Yes	Β3	Yes	C3	No
Α4	No	Β4	Yes	C4	No
Α5	No	Β5	Yes	C5	Yes
Α6	Yes	Β6	Yes	C6	No
Α7	Yes	Β7	Yes	C7	No
Α8	Yes	Β8	Yes	C8	No
A9	No	Β9	Yes	C9	No
A10	Yes	Β10	Yes	C10	No

Table 3 P values for each pair of groups’ comparison separately

	BGS vs OA group	BGS vs control group	OA vs control group
Surface	0.6531	0.6391	0.3611
Matrix	0.005	0.142	0
Cell distribution	0.001	0.049	0
Cell viability	1	0.146	0.146
Subchondral bone	0.03	0.285	0.024
Cartilage mineralization	0.031	0.3291	0.0001

¹These P values are calculated using the χ² test, while the others with Kruskal-Wallis or Mann-Whitney test. P < 0.05 was statistically significant. OA: Osteochondral autograft; BGS: Bone graft substitute.