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Opinion Review
Copyright: ©Author(s) 2026.
World J Orthop. Jun 18, 2026; 17(6): 119597
Published online Jun 18, 2026. doi: 10.5312/wjo.v17.i6.119597
Table 1 Stage-based management of Charcot neuroarthropathy
Stage
Clinical features
Main treatment
Stage 0Warmth, swelling, subtle imaging changesImmediate immobilization and offloading
Stage IFragmentation, active destructionNon-removable knee-high offloading, close monitoring
Stage IICoalescenceProtected progression, orthotic planning
Stage IIIConsolidated deformityCustom bracing or reconstruction if non-plantigrade/unstable
Table 2 Main fixation options for tibiotalocalcaneal fusion in Charcot hindfoot and ankle disease
Method
Advantages
Limitations
Retrograde intramedullary nailLoad sharing, spans ankle and subtalar joints, limited strippingImplant failure, nonunion, infection
Plate fixationAlignment control, useful when nailing unsuitableWider exposure, soft-tissue risk
External fixationUseful in infection or poor soft tissuePin-related problems, patient burden
Hybrid fixationAdded stability in selected salvage casesComplexity and limited evidence


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