Cardiovascular involvement in celiac disease

Table 1 Cardiovascular terms used for search in the study

Heart terms	Vascular terms
Afterload, preload	Angiogenesis
Arrhythmia, rhythm	Aorta, aortic
Atrial, atrium	Arterial, arteries, artery
Atrioventricular	Arteriosclerosis, atherosclerosis
Bachmann’s	Atherogenesis, atherogenic
Cardiac, cardio	Blood pressure
Cardiologist	Cardiovascular
Cardiomyopathies, cardiomyopathy	Circulatory
Congenital	Circumflex
Contractility	Coronary
Depolarization	Embolism
Effusion	Haemoptysis, hemoptysis
Ejection	Hemorrhage
Electromechanical	Haemodynamics, Hemodynamics
Endocardium, epicardium	Haemosiderosis, hemosiderosis
Fibrillation	Stroke
Foramen ovale	Thrombosis, thromboembolism
Frank-Starling	Vascular
Heart	Vein, veins
Infarction	Vena cava
Ischaemic, ischemic	Venous
Mitral	Venule, venules
Myocardial, myocardium
Myocarditis
Myocyte
Pericardial, pericardium
Purkinje
QT
Septum
Sinoatrial
Stenosis
Tachycardia
Tricuspid
Valve, valves, valvular

Table 2 Categories of published documents

Type	Description
Articles	Includes research articles, cohort studies and case control studies
Reviews	These included reviews of the literature and meta-analyses
Case studies	Limited to n = 1-3 patients in the study
Letters	These could include comments on other articles as well as case reports in letter form
Abstracts	When no full paper had been published, abstracts were included in the references
Editorials	These were typically comments on papers published in the same journal issue

Table 3 Types of studies associated with each keyword

Keyword	Article	Review	Case	Letter	Abstract	Editorial	Total
Arterial function	6	1	2	2			11
Atherosclerosis	4		1	5	3		13
Angiogenesis	6				1		7
Thrombosis	4	2	15	5	1		27
Stroke	2	2	7		1		12
Hemorrhage			7	3			10
Haemodynamics	1			1	2		4
Vascular - other	2		3				5
Pericardial effusion	2		1		1		4
Myocarditis	3	1	1	1			6
Cardiomyopathy	8	1	21	0	2	1	33
Infarction	4			1			5
Electromechanical	6				1		7
Ischemic heart disease	6			3	1	1	11
Rhythm disturbances	3		1	1	3		8
Congenital heart defect	3		1				4
Heart - other	3		2		1		6
Cardiovascular risk	11	2		1	3		17
Total	74	9	62	23	20	2	190

Table 4 Characteristics of the published studies by keyword

Category	Topic	Studies1	Median year	Range
Vascular	Arterial function	11	2014	2011-2016
Vascular	Atherosclerosis	13	2013	2008-2016
Vascular	Angiogenesis	7	2009	1970-2013
Vascular	Thrombosis	27	2007	1995-2016
Vascular	Stroke	12	2008	2001-2017
Vascular	Hemorrhage	10	2007	1997-2012
Vascular	Haemodynamics	4	1998	1993-2005
Vascular	Other	5	2004	1993-2013
Heart	Pericardial effusion	4	2008	2000-2014
Heart	Myocarditis	6	2004	2002-2012
Heart	Cardiomyopathy	33	2010	1986-2016
Heart	Infarction	5	2009	2008-2015
Heart	Electromechanical	7	2014	2008-2016
Heart	Ischemic heart disease	11	2014	2004-2016
Heart	Rhythm disturbances	8	2014	1989-2016
Heart	Congenital heart defect	4	2014	1982-2016
Heart	Other	6	2012	2004-2016
Cardiovas cular disease	Risk factors	17	2013	2007-2017

¹Studies: Total number of studies published on the topic. Studies could be used as references for more than one topic.