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©The Author(s) 2025.
World J Cardiol. Jun 26, 2025; 17(6): 106445
Published online Jun 26, 2025. doi: 10.4330/wjc.v17.i6.106445
Published online Jun 26, 2025. doi: 10.4330/wjc.v17.i6.106445
Table 1 Demographic Characteristics of study participants, n (%)
| Parameter | Value |
| Age (mean ± SD) (years) | 35.9 ± 3.38 |
| Sex | |
| Male | 88 (96.7) |
| Female | 3 (3.3) |
Table 2 Body mass index summary, n (%)
| Category (kg/m2) | |
| Underweight (< 18.5) | 0 |
| Healthy (18.5-24.9) | 19 (20.87) |
| Overweight (25-29.9) | 32 (35.16) |
| Obese (> 30) | 40 (43.9) |
| Body mass index (mean ± SD) | 30.7 ± 5.8 |
Table 3 Prevalence of cardiovascular risk factors, n (%)
| Risk factor | Measure | |
| Hypertension | Yes | 24 (26.37) |
| No | 67 (73.63) | |
| DM | Yes | 30 (32.97) |
| No | 61 (67.03) | |
| Type 1 DM | 2 (2.2) | |
| Type 2 DM | 28 (30.76) | |
| Newly diagnosed DM | 8 (8.79) | |
| Dyslipidemia | Yes | 63 (69.23) |
| No | 28 (30.76) | |
| Newly diagnosed dyslipidemia | 25 (39.68) | |
| Smoking status | Yes | 45 (49.45) |
| No | 46 (50.54) | |
| Family history of ischemic heart disease | Yes | 19 (20.88) |
| No | 72 (79.12) |
Table 4 Patient diagnosis on admission, n (%)
| Cause of admission | Measure | |
| STEMI | Yes | 52 (57.1) |
| No | 39 (42.86) | |
| Anterior STEMI | 35 (38.46) | |
| Inferior STEMI | 16 (17.58) | |
| Lateral STEMI | 1 (1.1) | |
| Non-STEMI | Yes | 39 (42.86) |
| No | 52 (57.1) |
Table 5 Echocardiographic findings, n (%)
| Parameter | |
| Segmental wall motion | |
| Normal | 17 (18.68) |
| Inferior/posterior hypokinesia | 20 (21.98) |
| Anterior-septal hypokinesia | 9 (10.99) |
| Apical akinesia | 6 (6.59) |
| Anterior and apical hypokinesia | 20 (21.98) |
| Global hypokinesia | 12 (13.19) |
| Lateral hypokinesia | 6 (6.59) |
| Ejection fraction range (mean ± SD) | 47.8% ± 12.92% |
Table 6 Coronary angiography findings, n (%)
| Parameter | n = 91 | |
| LM | Normal | 86 (94.51) |
| Significant lesion | 4 (4.4) | |
| Total occlusion (dissection) | 1 (1.1) | |
| LAD | Normal | 20 (21.98) |
| Significant lesion | 23 (25.28) | |
| Non-significant lesion | 12 (13.19) | |
| Total occlusion | 18 (19.78) | |
| Subtotal occlusion | 9 (9.89) | |
| Thrombus | 4 (4.39) | |
| Bridge | 3 (3.3) | |
| Total D1 | 2 (2.2) | |
| LCX | Normal | 51 (56.04) |
| Significant lesion | 16 (17.58) | |
| Non-significant lesion | 18 (19.78) | |
| Total occlusion | 3 (3.3) | |
| Subtotal occlusion | 2 (2.2) | |
| Dissection | 1 (1.1) | |
| RCA | Normal | 41 (45.05) |
| Significant lesion | 11 (12.09) | |
| Non-significant lesion | 20 (21.98) | |
| Total occlusion | 9 (9.89) | |
| Subtotal occlusion | 8 (8.79) | |
| Thrombus | 2 (2.2) | |
| Ramus | Normal | 86 (94.51) |
| Significant lesion | 1 (1.1) | |
| Non-significant lesion | 4 (4.4) | |
| n = 79 | ||
| Culprit artery | LAD | 51 (56.04) |
| RCA | 17 (18.68) | |
| LCX | 11 (12.09) | |
| n = 84 | ||
| Frequency of affected vessels | Single vessel disease | 66 (72.53) |
| Two vessel disease | 8 (8.79) | |
| Three vessel disease | 5 (5.49) | |
| LM + three vessel disease | 4 (4.4) | |
| LM + two vessel disease | 1(1.1) | |
Table 7 Coronary angiography final diagnosis, n (%)
| Final diagnosis | n = 91 |
| Obstructive CAD | 76 (83.51) |
| Myocardial infarction with non-obstructive coronary arteries | 13 (14.28) |
| Non-obstructive CAD | 5 (5.5) |
| Normal coronary | 6 (6.59) |
| Takotsubo cardiomyopathy | 1 (1.1) |
| Aortic valve insufficiency induced cardiomyopathy | 1 (1.1) |
| Coronary artery dissection | 2 (2.2) |
| With no obstructive lesion | 1 (1.1) |
| With obstructive lesion | 1 (1.1) |
Table 8 Management strategies, n (%)
| Conclusion | n = 91 | |
| Intervention | 78 (85.71) | |
| PCI | Total number | 68 (74.72) |
| PCI with 1 DES | 57 (62.64) | |
| PCI with 2 DES | 6 (6.59) | |
| PCI with 3 DES | 1 (1.1) | |
| PCI with 5 DES | 1 (1.1) | |
| PCI with 1 DES and 1 DEB | 1 (1.1) | |
| PCI with 2 DES and 1 DEB | 1 (1.1) | |
| PCI with 1 DES and 3 DEB | 1 (1.1) | |
| Thrombus aspiration | 2 (2.2) | |
| Open heart surgery | Total number | 8 (8.79) |
| MVD for CABG | 6 (6.59) | |
| MVD for CABG + AVR | 1 (1.1) | |
| AVR and Bentall procedure | 1 (1.1) | |
| Medical treatment | 6 (6.6) | |
| Normal coronaries | 7 (7.7) | |
Table 9 Summary of patient characteristics, n (%)
| Parameter | Value (n = 91) |
| Age (years, mean ± SD) | 35.9 ± 3.4 |
| Male | 88 (96.7) |
| Body mass index (kg/m²) (mean ± SD) | 30.7 ± 5.8 |
| Obese (> 30) | 40 (43.9) |
| Overweight (25–29.9) | 32 (35.2) |
| Risk factors | |
| Hyperlipidemia | 63 (69.2) |
| Smoking | 45 (49.5) |
| Diabetes mellitus | 30 (33.0) |
| Hypertension | 24 (26.4) |
| Family history of CAD | 18 (20.9) |
| Presentation | |
| STEMI | 52 (57.1) |
| Non-STEMI | 39 (42.9) |
| Coronary angiography findings | |
| Obstructive CAD | 76 (83.51) |
| Myocardial infarction with non-obstructive coronary arteries | 13 (14.28) |
| Coronary artery dissection | 2 (2.2) |
| Management | |
| Percutaneous intervention | 70 (76.92) |
| Surgery | 8 (8.79) |
| Medical treatment | 6 (6.6) |
| Normal coronaries | 7 (7.7) |
- Citation: Hegazi Abdelsamie A, Abdelhadi HO, Abdelwahed AT. Acute myocardial infarction in the young: A 3-year retrospective study. World J Cardiol 2025; 17(6): 106445
- URL: https://www.wjgnet.com/1949-8462/full/v17/i6/106445.htm
- DOI: https://dx.doi.org/10.4330/wjc.v17.i6.106445
