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©The Author(s) 2025.
World J Cardiol. Apr 26, 2025; 17(4): 102669
Published online Apr 26, 2025. doi: 10.4330/wjc.v17.i4.102669
Published online Apr 26, 2025. doi: 10.4330/wjc.v17.i4.102669
Table 1 Cohort characteristics, median (25th-75th percentiles)
Sutured (n = 808) | Perceval (n = 174) | P value | |
Demographics | |||
Age (n = 982) | 70 (64-76) | 77 (74-80) | < 0.001 |
Gender (n = 982) | < 0.001 | ||
Male | 520 (64.4) | 70 (40.2) | |
Female | 288 (35.6) | 104 (59.8) | |
BMI (n = 982) | 28.4 (25.0-32.4) | 29.0 (25.6-32.8) | 0.165 |
Smoking status (n = 848) | 0.024 | ||
Non-smoker | 334 (41.3) | 65 (37.4) | |
Ex-smoker | 279 (34.5) | 76 (43.7) | |
Current smoker | 86 (10.6) | 8 (4.6) | |
Diabetes (n = 982) | 0.002 | ||
No | 659 (81.6) | 124 (71.3) | |
Diet | 38 (4.7) | 7 (4.0) | |
Oral therapy | 79 (9.8) | 27 (15.5) | |
Insulin | 32 (4.0) | 16 (9.2) | |
NYHA grade (n = 879) | 0.148 | ||
Grade I | 144 (17.8) | 21 (12.1) | |
Grade II | 208 (25.7) | 37 (21.3) | |
Grade III | 282 (34.9) | 69 (39.7) | |
Grade IV | 93 (11.5) | 25 (14.4) | |
Cardiovascular risk factors | |||
Heart rhythm (n = 914) | 0.54 | ||
Sinus rhythm | 607 (80.8) | 129 (79.1) | |
Atrial fibrillation/flutter | 123 (16.4) | 32 (19.6) | |
Complete heart block/pacing | 11 (1.5) | 2 (1.2) | |
Other dysrhythmia | 9 (1.2) | 0 (0.0) | |
Hypertension (n = 882) | 511 (63.2) | 126 (72.4) | 0.022 |
CCS angina status (n = 858) | 0.863 | ||
CCS0 | 422 (59.1) | 79 (54.9) | |
CCS1 | 83 (11.6) | 19 (13.2) | |
CCS2 | 95 (13.3) | 23 (16.0) | |
CCS3 | 82 (11.5) | 16 (11.1) | |
CCS4 | 32 (4.5) | 7 (4.9) | |
LVEF (n = 681) | 0.578 | ||
Good (> 50%) | 424 (75.7) | 92 (76.0) | |
Moderate (21%-30%) | 109 (19.5) | 22 (18.2) | |
Poor (31%-50%) | 22 (3.9) | 7 (5.8) | |
Very poor (< 25%) | 5 (0.9) | 0 (0.0) | |
Previous MI (n = 918) | 62 (8.2) | 12 (7.5) | 0.794 |
Reoperation procedure (n = 982) | 42 (5.2) | 7 (4.0) | 0.518 |
Risk scores | |||
Additive Euroscore (n = 980) | 5.00 (1.88-7.00) | 6.00 (2.22-7.00) | 0.003 |
Logistic Euroscore (n = 600) | 5.28 (3.29-8.56) | 7.01 (5.48-10.27) | < 0.001 |
Table 2 Intra-operative details before and after propensity matching, median (25th-75th percentiles)
Before propensity score matching | After propensity score matching | |||||
Sutured | Perceval | P value | Sutured | Perceval | P value | |
Bypass time (minutes) (n = 925) | 93.0 (72.0-123) | 60.0 (49.0-78.0) | < 0.001 | 87.0 (69.0-112) | 60.0 (49.0-78.0) | < 0.001 |
Cross-clamp time (minutes) (n = 924) | 75.0 (58.0-99.0) | 45.5 (36.0-57.0) | < 0.001 | 71.0 (56.0-90.6) | 45.5 (36.0-57.0) | < 0.001 |
Time Ventilated (hours) (n = 873) | 11.5 (7.6-19.0) | 9.9 (7.3-17.9) | 0.383 | 13.6 (9.35-20.5) | 9.88 (7.33-17.9) | 0.005 |
Time in theatre (minutes) (n = 981) | 180 (153-215) | 139 (119-165) | < 0.001 | 171 (143-201) | 139 (119-165) | < 0.001 |
Table 3 Immediate post-operative outcomes before and after propensity score matching, median (25th-75th percentiles)
Before propensity score matching | After propensity score matching | Odds ratio1 | |||||
Sutured valves | Perceval valves | P value | Sutured valves | Perceval valves | P value | ||
Intra-operative mortality | 0 (0.0) | 0 (0.0) | NA | 0 (0.0) | 0 (0.0) | NA | NA |
In-hospital mortality | 16 (2.0) | 1 (0.6) | 0.197 | 2 (1.1) | 1 (0.6) | 0.562 | 0.50 (0.04-5.55) |
< 30 days mortality | 23 (2.8) | 3 (1.7) | 0.403 | 4 (2.3) | 3 (1.7) | 0.703 | 0.73 (0.16-3.35) |
Length of CICU stay (days) (n = 917) | 1.14 (0.97-2.11) | 1.13 (0.98-1.91) | 0.543 | 1.25 (1.00-2.50) | 1.13 (0.96-2.00) | 0.132 | NA |
Total length of stay (days) (n = 917) | 6.90 (5.31-9.99) | 7.08 (5.93-9.90) | 0.248 | 8 (6.00-11.0) | 7 (6.00-10.00) | 0.315 | NA |
Post-operative complications | |||||||
Atrial fibrillation | 229 (28.3) | 39 (22.4) | 0.111 | 58 (33.3) | 39 (22.4) | 0.023 | 0.57 (0.35-0.91) |
Pneumonia | 152 (18.8) | 21 (12.1) | 0.030 | 36 (20.7) | 21 (12.1) | 0.030 | 0.49 (0.27-0.90) |
Delirium | 100 (12.4) | 28 (16.1) | 0.187 | 27 (15.5) | 28 (16.1) | 0.883 | 1.03 (0.58-1.83) |
MI | 1 (0.1) | 0 (0.0) | 0.642 | 0 (0.0) | 0 (0.0) | NA | NA |
PPM | 19 (2.4) | 6 (3.4) | 0.405 | 4 (3.10) | 6 (3.4) | 0.521 | 1.50 (0.42-5.44) |
VT/VF | 9 (1.1) | 0 (0.0) | 0.162 | 0 (0.0) | 0 (0.0) | NA | 0.94 (0.06-15.9) |
Pneumothorax | 8 (1.0) | 1 (0.6) | 0.602 | 1 (0.6) | 1 (0.60) | 1.000 | 0.95 (0.06-15.89) |
Stroke | 25 (3.1) | 6 (3.4) | 0.808 | 4 (2.3) | 6 (3.4) | 0.521 | 1.51 (0.42-5.47) |
- Citation: French T, Avtaar Singh SS, Giordano V, Koutsogiannidis CP, Lim KHH, Pessotto R, Zamvar V. Sutureless aortic valve and post-operative atrial fibrillation: Five-year outcomes from a propensity matched cohort study. World J Cardiol 2025; 17(4): 102669
- URL: https://www.wjgnet.com/1949-8462/full/v17/i4/102669.htm
- DOI: https://dx.doi.org/10.4330/wjc.v17.i4.102669