Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm

Figure 1 Myeloproliferative diseases in predisposing to acute coronary syndrome: The Virchow triad. Myeloproliferative neoplasms (MPNs) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. Patients with MPN are at high risk of cardiovascular events, especially those sustained by arterial thrombosis. Different causal links have been recently shown to account for increased acute myocardial infarction risk in patients with MPNs. ACS: Acute coronary syndrome; MPNs: Myeloproliferative neoplasms.