Role of microRNAs in translation regulation and cancer

doi:10.4331/wjbc.v8.i1.45

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World Journal of Biological Chemistry

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World J Biol Chem. Feb 26, 2017; 8(1): 45-56
Published online Feb 26, 2017. doi: 10.4331/wjbc.v8.i1.45

Table 1 List of selected tumor suppressor microRNAs and oncomiRs in cancer

	Cancer type
OncomiRs
miR17-92[108]	B-cell lymphoma, small cell lung cancer, colon cancer, gastric cancer
miR-21[107]	Breast, colon and lung cancer, glioblastoma
miR-106[133]	Gastric cancer, colorectal cancer
miR-10b[113]	Breast cancer
miR-191[134,135]	Human colorectal and breast cancer
Tumor suppressor miRNAs
let-7[105,106]	Lung cancer, Burkitt lymphoma
miR-15a, miR16-1[103,104]	CLL, prostate cancer, mesothelioma
miR-29[136]	Lung cancer, breast cancer
miR-34a[116]	Prostate cancer, mesothelioma, HCC
miR-126[114]	Lung and breast cancer
Both O and TS
miR-24[137,138]	Breast cancer, glioma (O)
miR-24[137,138]	Laryngeal carcinoma (TS)
miR-125[122,123]	Pancreatic and prostate cancer (O)
miR-125[122,123]	Melanoma, osteosarcoma, ovarian cancer (TS)
miR-155[120,121]	Lymphoma, breast cancer (O)
miR-155[120,121]	Melanoma, ovarian and gastric cancer (TS)
miR-221/222[139]	Glioblastoma, HCC, breast cancer (O)
miR-221/222[139]	Tongue squamous cell carcinoma (TS)

CLL: Chronic lymphocytic leukemia; HCC: Hepatocellular carcinoma; O: OncomiR; TS: Tumor suppressor miRNA.

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Citation: Oliveto S, Mancino M, Manfrini N, Biffo S. Role of microRNAs in translation regulation and cancer. World J Biol Chem 2017; 8(1): 45-56
URL: https://www.wjgnet.com/1949-8454/full/v8/i1/45.htm
DOI: https://dx.doi.org/10.4331/wjbc.v8.i1.45