Anticancer potential of Ferula assa-foetida and its constituents, a powerful plant for cancer therapy

doi:10.4331/wjbc.v14.i2.28

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Mar 27, 2023 (publication date) through Jan 8, 2025

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Mar 27, 2023; 14(2): 28-39
Published online Mar 27, 2023. doi: 10.4331/wjbc.v14.i2.28

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Figure 1 Chemical structure of some sulfide compounds derived from Ferula assa-foetida.

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Figure 2 Chemical structure of isolated constituents from Ferula assa-foetida showed anticancer effect.

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Figure 3 Investigated mechanisms by which Ferula assa-foetida exerts its anticancer effects. BCL2: B-cell lymphoma 2; CDKs: Cyclin-dependent kinases; EMT: Epithelial-mesenchymal transition; MMPS: Matrix metalloproteinases; VEGF: Vascular endothelial growth factor; VEGFR: Vascular endothelial growth factor receptor; ROS: Reactive oxygen species.

Citation: Sirizi MAG, Alizadeh Ghalenoei J, Allahtavakoli M, Forouzanfar H, Bagheri SM. Anticancer potential of Ferula assa-foetida and its constituents, a powerful plant for cancer therapy. World J Biol Chem 2023; 14(2): 28-39
URL: https://www.wjgnet.com/1949-8454/full/v14/i2/28.htm
DOI: https://dx.doi.org/10.4331/wjbc.v14.i2.28