International scientific communications in the field of colorectal tumour markers

Table 1 General bibliometric characteristics of four data-bases concerning the topic

Parameter	WoS	BIOSIS	MEDLINE	Scopus
Total number of publications	1587	1172	1108	1221
Total number of journals	334	265	364	N/A
Total number of journals with one article only	163	140	201	N/A
Total number of languages (n = 21)	5	11	17	19
Total number of countries of authors (n = 70)	63	55	N/A	63
Total number of research areas (WoS categories)	48	42	49	21

N/A: Not available.

Table 2 Document type distribution in four data-bases

Document type	WoS	BIOSIS	MEDLINE	Scopus
Journal article	870	700	1057	970
Review	63	38	118	114
Congress proceedings	57	6	1	39
Meeting abstract	543	313	0	0
Editorial	34	6	17	18
Letter-to-the-editor	37	9	28	32
Book chapter	6	9	0	8
Evaluation study	0	0	28	0
Multicenter study	0	0	19	0
Randomized controlled trial	0	0	15	0
Meta-analysis	0	0	13	0
Validation study	0	0	11	0
Patent	0	19	0	0

Table 3 Language distribution of publications on the topic abstracted in four data-bases

Language	WoS	BIOSIS	MEDLINE	Scopus
English	1545	1136	1017	1095
German	17	5	10	17
French	14	9	12	14
Spanish	9	2	9	12
Japanese	0	7	17	21
Chinese	0	6	11	27
Italian	2	1	6	7
Polish	0	0	5	7
Czech	0	1	4	5
Danish	0	0	4	4
Other (11)	0	3 (5)	7 (15)	9 (15)

Table 4 “Core” journals on the topic in four data-bases

Rank	Journal title	WoS	BIOSIS	MEDLINE	Scopus
1	Gastroenterology	115	100	15	15
2	J Clin Oncol	96	4	12	13
3	Br J Cancer	52	47	45	47
4	Anticancer Res	46	54	39	39
5	Cancer Res	43	45	14	14
6	Eur J Cancer	38	36	20	20
7	Clin Cancer Res	36	9	34	34
8	Dis Colon Rectum	33	4	24	19
9	Oncol Rep	28	28	28	28
10	Int J Cancer	27	25	26	26
Total "core" journals - n (%)		10 (2.99)	10 (3.76)	10 (2.75)	10 (N/A)
Total publications - n (%)		514 (32.39)	352 (30.03)	255 (23.01)	257 (21.05)

N/A: Not available.

Table 5 Most productive authors on the topic in four data-bases

Rank	Author’s name	WoS	BIOSIS	MEDLINE	Scopus
1	Ahlquist DA	25	31	10	8
2	Mori M	22	14	16	20
3	Doki Y	17	11	13	16
4	Nielsen HJ	17	12	2	11
5	Lugli A	16	14	5	6
6	Mimori K	16	10	11	14
7	Zlobec I	16	14	5	6
8	Inoue Y	14	4	10	10
9	Ishi H	14	8	11	14
10	Mahoney DW	14	11	1	2

Table 6 Most productive authors - inventors on the topic in Derwent

Name	Country	City	Institution	Patents
Karl J	Germany	Penzberg	Roche Diagnostic GmbH	9
Choquet- Kastylevsky G	France	Nancy Letoile	Biomerieux SA	9
Charrier JP	France	Nancy Letoile	Biomerieux SA	9
Ataman-Oenal Y	France	Nancy Letoile	Biomerieux SA	6
Beaulieu C	France	Nancy Letoile	Biomerieux SA	6
Ahlquist DA	United States	Rochester	Mayo Clinic	4

Table 7 Most productive institutions on the topic in WoS and in Scopus

Rank	Institution	WoS	Scopus
1	German Cancer Research Center	29	26
2	Mayo Clinic	29	17
3	Harvard University	28	14
4	Osaka University	25	25
5	Kyushu University	22	22
6	Universität Heidelberg	25	19
7	Ludwig-Maximilians-Universität München	21	23
8	Memorial Sloan-Kettering Cancer Center	20	12
9	Kaohsiung Medical University	15	22
10	University of Copenhagen	23	9

Table 8 Most productive institutions - assignees on this topic in Derwent

Nomination	Country	Patents
Biomerieux SA	France	9
Hoffmann La Roche	Switzerland	9
Mayo Medical Education and Research	United States	4
Ruiqu Biotechnology Shanghai Co. Ltd	China	3
Signature Diagnostics GmbH	Germany	3
Shimadzu Corporation	Japan	3
Ver Christelijk Wetenschappel Onderw	The Netherlands	3
Fudan University	China	3

Table 9 Dominant research areas (WoS categories) on the topic in three data-bases

Rank	Research area (WoS category)	WoS	BIOSIS	MEDLINE
1	Oncology	834	1153	1034
2	Gastroenterology and hepatology	297	1084	166
3	Surgery	301	55	132
4	Pathology	169	55	74
5	Cell biology	47	42	231
6	Biochemistry and molecular biology	42	266	703
7	Medical laboratory technology	33	393	48
8	Pharmacology and pharmacy	27	144	190
9	Radiology, nuclear medicine and medical imaging	25	15	30
10	Genetics and heredity	24	402	490
11	Public, environmental and occupational health	23	22	29
12	Immunology	10	77	454
13	Hematology	7	22	43
14	Nutrition and dietetics	5	16	17
15	Endocrinology and metabolism	3	98	22

Table 10 Cumulative citation patterns on the topic in WoS and BIOSIS

Citation parameter	WoS	BIOSIS
Total number of publications	1587	1172
Sum of the times cited	25116	13297
Sum of the times cited without self-citations	24092	12777
Percentage of these times cited	95.92	96.09
Citing articles	19607	11061
Citing articles without self-citations	19120	10779
Percentage of these citing articles	97.52	97.45
Average citations per item	15.83	11.35
Average citations per year	810.19	443.23
Articles cited at least once	961	643
Percentage of these articles	60.55	54.86
H-index	75	57

Table 11 Ten most cited articles on the topic in three data-bases

Ref.	Journal title, volume, year and pages	WoS	BIOSIS	Scopus
Ng et al[14]	Gut 2009; 58: 1375-1381	593	447	656
Bast et al[15]	J Clin Oncol 2001; 19: 1865-1878	552	314	670
Cui et al[16]	Science 2003; 299: 1753-1755	472	400	530
No author list[17]	J Clin Oncol 1996; 14: 2843-2877	388	234	Absent
Walther et al[18]	Nat Rev Cancer 2009; 9: 489-499	315	243	348
Duffy[19]	Clin Chem 2001; 47: 624-630	253	141	289
Duffy et al[20]	Eur J Cancer 2007; 43: 1348-1360	245	160	276
Nakamori et al[21]	Gastroenterology 1994; 106: 353-361	234	179	219
Sturgeon et al[22]	Clin Chem 2008; 54: E11-E79	211	Absent	255
Duffy et al[23]	Eur J Cancer 2003; 39: 718-727	202	120	235

Table 12 Bibliometric characteristics of scientific forums on the topic in WoS and BIOSIS

Parameter	WoS	BIOSIS
Number of forum titles	95	73
Number of unique forums	170	203
Number of publications	377	432
Number of forums with a single event only	71	52
Number of forums with two events	9	5
Number of forums with three events	5	2
Number of forums with one publication only	57	117
Number of forums with two publications	10	34
Number of forums with three publications	5	16
Maximal number of events of a unique forum	12	27
Maximal number of publications in a unique forum	58	102

Table 13 Scientific forums with most events and papers in them on the topic in WoS and BIOSIS

Scientific forum title	WoS		BIOSIS
	Events	Papers	Events	Papers
Digestive Disease Week	12	58	25	90
Annual Meeting of the American Association for Cancer Research	4	17	27	102
Annual Meeting of the United States and Canadian Academy of Pathology	10	34	11	29
Annual Meeting of the American Society of Clinical Oncology	8	49	0	0
European Society for Medical Oncology Congress	7	17	1	5
World Congress of Gastrointestinal Cancer	7	24	0	0
Meeting of the International Society for Oncodevelopmental Biology and Medicine	3	6	9	16
Meeting of the Pathological Society of Great Britain and Ireland	5	5	11	11
European Congress of Pathology	0	0	11	22
Annual Meeting of the American College of Gastroenterology	4	5	5	6

Table 14 Scientific forums with “tumour or cancer (bio)markers” in their titles in WoS and BIOSIS

Scientific forum title	WoS		BIOSIS
	Events	Papers	Events	Papers
Hamburg Symposium on Tumor Markers	2	3	5	8
Congress (Meeting) of the International Society of Oncology and Biomarkers	3	4	2	2
Annual Meeting of the EORTC/NCI/ASCO on Molecular Markers in Cancer	1	2	1	2
Annual Conference on Diet and Cancer: Markers, Prevention, and Treatment	1	1	0	0
International Symposium on Tumor Markers - From Biology to Therapy	1	1	0	0
Joint Meeting on Markers in Cancer of ASCO, EORTC and NCI	0	0	1	1

Table 15 Specialized journals with the term of “(bio)markers” in their titles in four data-bases

Rank	Journal title	WoS	Scopus	MEDLINE	BIOSIS	Total
1	Cancer Epidemiol Biomarkers Prev	0	0	0	15	15
2	Int J Biol Markers	5	0	11	9	131
3	Cancer Biomarkers	7	8	7	8	81
4	Disease Markers	5	5	5	5	51
5	J Tumor Marker Oncol	0	3	0	6	61
6	Biomarkers	2	0	2	2	21
7	Biomarkers Med	0	0	1	0	1
8	Genet Testing Mol Biomarkers	1	0	1	0	11
Total number of publications		20	16	27	45	511
Total number of journals		5	3	6	6	81
Countries of authors		19	13	20	20	251
Countries of journals		5	2	4	5	51
Articles in domestic journals		2	1	2	14	111
Articles in journals published abroad		18	15	25	31	401

¹The sum of unique items is smaller than the total amount of single items due their duplication in several data-bases.