Pathological factors affecting gastric adenocarcinoma survival in a Caribbean population from 2000-2010

Table 1 Clinical characteristics

Characteristic		n (%)
Gender	Male	36 (45.6 )
	Female	43 (54.4 )
Number of previous gastrectomies by surgeon	< 10	30 (38.0 )
	> 10	49 (62.0)
Patient status	Alive	7 (8.9)
	Censored	40 (50.6)
	Dead	32 (40.5)

Table 2 Tumour location n (%)

Location of tumour		n = 79
Lesser curvature	Uninvolved	60 (75.3)
	Involved	19 (24.7)
Greater curvature	Uninvolved	70 (88.3)
	Involved	9 (11.7)
Antrum	Uninvolved	35 (45.5)
	Involved	34 (54.5)
Pylorus	Uninvolved	49 (62.3)
	Involved	50 (37.7)
Body	Uninvolved	62 (79.2)
	Involved	17 (20.8)
Cardia	Uninvolved	71 (90.9)
	Involved	8 (9.1)
Fundus	Uninvolved	73 (92.2)
	Involved	6 (7.8)
Anterior wall	Uninvolved	66 (84.4)
	Involved	13 (15.6)
Posterior wall	Uninvolved	59 (75.3)
	Involved	20 (24.7)
Circumferential	Uninvolved	66 (83.1)
	Involved	13 (16.9)

Table 3 Pathological characteristics

Gross appearance		Percentage
Configuration	Ulcerative	56.00
	Infiltrative	22.70
	Exophytic	21.30
	n	75
Gross location
Proximal	Uninvolved	88.20
	Involved	11.80
	n	76
Distal	Uninvolved	84.20
	Involved	15.80
	n	76
Histological appearance
Intestinal	No	42.60
	Yes	57.40
	n	68
Differentiation	Poor	43.40
	Moderate	50.90
	Well	5.70
	n	53
Grade	Low	43.20
	Moderate	32.40
	High	24.30
Maximum extent of invasion through stomach wall
Mucosa	Involved	100.00
	n	78
Muscularis propria	Uninvolved	3.80
	Involved	96.20
	n	78
Sub–Serosa	Uninvolved	9.00
	Involved	91.00
	n	78
Serosa	Uninvolved	13.30
	Involved	86.70
Histological appearance
Venous infiltration	Absent	51.90
	Present	48.10
	n	52
Perineural infiltration	Absent	40.00
	Present	60.00
	n	35
H. Pylori	Absent	80.50
	Present	19.50
	n	77
Chronic active gastritis	Absent	96.20
	Present	3.80
	n	78
Chronic gastritis	Absent	59.00
	Present	41.00
	n	78
Chronic multifocal Atrophic gastritis	Absent	70.50
	Present	29.50
	n	78

Table 4 Logrank test of survival functions

Variable	P value
Gender	0.9688
Number of gastrectomies previously performed	0.6725
Lesser curvature	0.9716
Greater curvature	0.7928
Antrum	0.2613
Pylorus	0.2486
Body	0.2581
Cardia	0.0577
Fundus	0.9704
Anterior wall	0.3977
Posterior wall	0.9507
Circumferential	0.0370
Diffuse	0.9389
Intestinal	0.6020
Grade	0.2436
Configuration	0.2598
Differentiation	0.2416

Table 5 Single predictor cox regression models

Predictor	HR	P value	95%CI
Cardia
Involved vs uninvolved	2.685	0.069	0.927	7.779
Circumferential
Involved vs uninvolved	2.424	0.044	1.025	5.732
Venous infiltration
Present vs absent	2.502	0.055	0.98	6.384
Age	1.007	0.643	0.978	1.037
Size	0.992	0.897	0.877	1.122
Positive lymph nodes	1.059	0.118	0.986	1.137
Total lymph nodes removed	0.981	0.603	0.911	1.055
Type of surgery
Total gastrectomy vs subtotal gastrectomy	1.45	0.417	0.591	3.553
Presence of Helicobacter pylori	0.456	0.198	0.138	1.508