Effect of Daikenchuto (TJ-100) on abdominal bloating in hepatectomized patients

Table 1 Patient characteristics n (%)

Variable
Age (yr)	64.9 ± 6.7
Male/female	15/3
Height (cm)	161.4 ± 10.5
Weight (kg)	60.6 ± 9.9
BMI (%)	23.3 ± 3.7
Diagnosis
HCC	12 (67)
MLT	5 (28)
CCC	1 (5)
Child-Pugh score
A	18 (100)
B	0 (0)
C	0 (0)

Data are presented as mean ± SD. BMI: Body-mass index; HCC: Hepatocellular carcinoma; MLT: Metastatic liver tumor; CCC: Cholangiocarcinoma.

Table 2 Risk factors for worse gastrointestinal symptoms rating scale score after hepatic resection in patients treated with Daikenchuto

Variable	P value
Use of lactulose (yes/no)	0.001
Preserved liver function (ChE)	0.115
Marker of liver fibrosis (hyarulonic acid)	0.553
Intraoperative blood loss (mL)	0.080
Type of hepatic resection1	0.093
BMI	0.192
Operation time (min)	0.466
Anesthesia time (min)	0.556

¹Right lobectomy, left lobectomy, segmentectomy, or wedge resection. BMI: Body-mass index; ChE: Choline esterase.

Table 3 Patient characteristics of Daikenchuto group and Daikenchuto + lactulose group (mean ± SD)

Variable	DKT group	DKT + lactulose group	P value
Age (yr)	65.9 ± 6.1	64.0 ± 7.6	0.567
Male/female	7/2	8/1	1.000
Height (cm)	164.6 ± 7.3	158.2 ± 12.6	0.206
Weight (kg)	65.1 ± 7.4	56.1 ± 10.5	0.052
BMI (%)	24.0 ± 1.7	22.6 ± 5.0	0.455
Child-Pugh score	Grade A: 9	Grade A: 9	0.585
CLIP score	Score 0: 8 and Score 1: 1	Score 0: 7 and Score 1: 2	1.000
Liver damage score	Grade A: 9	Grade A: 7 and Grade B: 2	0.166
Type of hepatic resection			0.188
	Right lobectomy: 1	Left lobectomy: 1
	Segmentectomy: 1	Segmentectomy: 3
	Wedge resection: 7	Wedge resection: 5
Intraoperative blood loss (mL)	428.9 ± 294.0	852.2 ± 928.4	0.211
Operation time (min)	307.8 ± 107.5	347.2 ± 125.0	0.483
Anesthesia time (min)	392.8 ± 118.0	420.6 ± 128.4	0.639

BMI: Body-mass index; DKT: Daikenchuto.