Laparoscopic sleeve gastrectomy combined with montelukast for obese patients with secretory otitis media

doi:10.4240/wjgs.120692

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jun 27, 2026; 18(6): 120692
Published online Jun 27, 2026. doi: 10.4240/wjgs.120692

Table 1 Comparison of general information, n (%)/mean ± SD

Group	n	Age (years)	Gender		OME disease course (months)	BMI (kg/m²)
Group	n	Age (years)	Male	Female	OME disease course (months)	BMI (kg/m²)
Control group	48	35.60 ± 8.60	18 (37.50)	30 (62.50)	8.25 ± 3.85	35.71 ± 3.94
Observation group	64	36.30 ± 9.18	26 (40.63)	38 (59.37)	8.36 ± 4.21	36.11 ± 4.15
t/χ²		0.406	0.112		0.141	0.520
P value		0.685	0.738		0.888	0.604

OME: Otitis media with effusion; BMI: Body mass index.

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Table 2 Comparison of weight loss indicators at different time points after surgery, mean ± SD

Group	n	%TWL		%EWL
Group	n	1 month after surgery	6 months after surgery	1 month after surgery	6 months after surgery
Control group	48	9.26 ± 2.15	21.20 ± 4.87	18.87 ± 4.01	42.31 ± 6.15
Observation group	64	9.43 ± 2.34	21.76 ± 4.21	19.08 ± 4.10	44.16 ± 6.74
t		0.387	0.655	0.276	1.487
P value		0.700	0.514	0.783	0.140

%TWL: Percentage of total weight loss; %EWL: Percentage of excess weight loss.

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Table 3 Comparison of the time for middle ear effusion to resolve, and the improvement in hearing and eustachian tube function, mean ± SD

Group	n	Time for fluid accumulation to subside (days)	Air-bone conductance difference (dB)		ETDQ-7 (points)
Group	n	Time for fluid accumulation to subside (days)	Preoperative	1 month after surgery	Preoperative	1 month after surgery
Control group	48	42.10 ± 8.32	28.56 ± 6.39	22.04 ± 4.57^a	4.54 ± 1.22	3.75 ± 1.16^a
Observation group	64	28.39 ± 6.51	29.09 ± 5.95	18.92 ± 4.65^a	4.47 ± 1.17	2.63 ± 0.97^a
t		9.787	0.453	3.539	0.321	5.595
P value		< 0.001	0.651	0.001	0.749	< 0.001

^aP < 0.05 vs preoperative values in this group.

ETDQ-7: Eustachian Tube Dysfunction Questionnaire-7.

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Table 4 Comparison of quality of life before and after surgery, mean ± SD (points)

Group	n	Preoperative	1 month after surgery	3 months after surgery
Control group	48	37.48 ± 3.56	51.34 ± 5.34^a	60.33 ± 5.33^a
Observation group	64	36.27 ± 3.23	54.29 ± 5.43^a	63.23 ± 5.42^a
t		1.882	2.872	2.829
P value		0.062	0.005	0.006

^aP < 0.05 vs preoperative values in this group.

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Table 5 Comparison of adverse reactions and complications, n (%)

Group	n	Surgical complications	Drug-related adverse reactions	Overall incidence
Control group	48	2 (4.17)	0 (0.00)	2 (4.17)
Observation group	64	1 (1.56)	4 (6.25)	5 (7.81)
χ²		0.714	3.111	0.622
P value		0.398	0.078	0.430

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Citation: Qiang HL, Yao XL, Jiang ZF, Wang W. Laparoscopic sleeve gastrectomy combined with montelukast for obese patients with secretory otitis media. World J Gastrointest Surg 2026; 18(6): 120692
URL: https://www.wjgnet.com/1948-9366/full/v18/i6/120692.htm
DOI: https://dx.doi.org/10.4240/wjgs.120692

Qiang HL, Yao XL, Jiang ZF, Wang W. Laparoscopic sleeve gastrectomy combined with montelukast for obese patients with secretory otitis media. World J Gastrointest Surg 2026; 18(6): 120692 [DOI: 10.4240/wjgs.120692]

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