Copyright: ©Author(s) 2026.
World J Gastrointest Surg. Jun 27, 2026; 18(6): 118262
Published online Jun 27, 2026. doi: 10.4240/wjgs.118262
Published online Jun 27, 2026. doi: 10.4240/wjgs.118262
Table 1 Dynamic changes in liver function tests
| Parameter1 | Preoperative | POD 1 | POD 3 | POD 10 (discharge) |
| ALT (U/L) | 131.0 | 80.0 | 53.2 | 34.4 |
| AST (U/L) | 97.2 | 37.9 | 22.1 | 18.3 |
| Total bilirubin (μmol/L) | 6.2 | 3.0 | 5.7 | 3.0 |
| Direct bilirubin (μmol/L) | 4.42 | 2.70 | 1.5 | 0.8 |
| Albumin (g/L) | 34.6 | 33.5 | 35.0 | 37.1 |
| Total protein (g/L) | 53.2 | 52.2 | 54.8 | 64.5 |
| C-reactive protein (mg/L) | 46.9 | 55.0 | 30.0 | 10.0 |
Table 2 Timeline of clinical events
| Time | Event |
| 6 months pre-admission | Onset of progressive vomiting, early satiety, and unintentional weight loss |
| Admission | Hospital admission with clinical confirmation of gastric outlet obstruction |
| Diagnostic workup | Magnetic resonance imaging and contrast upper gastrointestinal study |
| Surgery | Distal gastrectomy with Billroth II reconstruction and cholecystectomy |
| Postoperative day 10 | Discharge in satisfactory condition |
| Follow-up | Complete resolution of symptoms and restoration of oral intake |
Table 3 Comparison of open vs laparoscopic surgery in Mirizzi syndrome (literature-based)
| Parameter | Open surgery | Laparoscopic surgery |
| Typical indication | Advanced Mirizzi syndrome (type III-V/Vb), cholecystoenteric fistula | Selected early-stage cases |
| Preoperative diagnosis | Often uncertain; diagnosis frequently established intraoperatively | Similar limitations |
| Technical feasibility | High due to direct anatomical control | Limited in advanced disease |
| Conversion rate | Not applicable | High in advanced stages |
| Perioperative mortality | Low | Low |
| Procedure-related morbidity | Acceptable; mainly related to disease severity | Higher in advanced disease |
| Risk of bile duct injury | Lower with controlled dissection | Increased in distorted anatomy |
| Recurrence of biliary symptoms | Low after definitive surgery | Variable |
| Long-term outcome | Generally favorable | Favorable only in selected cases |
- Citation: Mussina A, Berik D, Birzhanbekov N, Kaniyev S, Baimakhanov B. Mirizzi syndrome type Vb with cholecystogastric fistula causing gastric outlet obstruction: A case report. World J Gastrointest Surg 2026; 18(6): 118262
- URL: https://www.wjgnet.com/1948-9366/full/v18/i6/118262.htm
- DOI: https://dx.doi.org/10.4240/wjgs.118262