Nomogram construction and validation for predicting infection recurrence after necrotic tissue debridement in severe acute pancreatitis

Table 1 Comparison of baseline data between the two groups, n (%)/(mean ± SD)

	Relapse group (n = 55)	The non-relapse group (n = 163)	t/χ2	P value
Age (years)	62.15 ± 6.23	59.32 ± 7.15	2.969	0.003
Gender			0.247	0.619
Male	32 (58.18)	101 (61.96)
Female	23 (41.82)	62 (38.04)
BMI (kg/m2)	24.82 ± 3.17	24.95 ± 2.86	0.284	0.777
Smoking history			0.667	0.414
Have	24 (43.64)	61 (37.42)
None	31 (56.36)	102 (62.58)
Drinking history			0.210	0.647
Have	18 (32.73)	48 (29.45)
None	37 (67.27)	115 (70.55)
History of diabetes			7.690	0.006
Have	21 (38.18)	32 (19.63)
None	34 (61.82)	131 (80.37)
History of hypertension			0.685	0.408
Have	23 (41.82)	58 (35.58)
None	32 (58.18)	105 (64.42)
APACHE II score (scores)	15.98 ± 1.46	10.91 ± 1.85	18.466	< 0.001
CTSI score (scores)	8.27 ± 1.18	5.06 ± 0.84	22.034	< 0.001
CRP (mg/L)	116.53 ± 19.03	74.21 ± 13.82	17.751	< 0.001
PCT (μg /L)	3.41 ± 0.81	2.59 ± 0.61	7.900	< 0.001
ALB (g/L)	30.15 ± 3.19	36.13 ± 2.47	14.386	< 0.001
Amylase (U/L)	728.06 ± 106.64	728.38 ± 112.36	0.018	0.985
Lipase (U/L)	128.32 ± 20.21	126.88 ± 20.15	0.458	0.647
Operation duration (minutes)	105.80 ± 12.68	103.48 ± 12.62	1.181	0.239
Intraoperative blood loss (mL)	131.67 ± 14.82	135.63 ± 20.27	1.332	0.184

BMI: Body mass index; APACHE: Acute Physiology and Chronic Health Evaluation; CTSI: Computed tomography severity index; CRP: C-reactive protein; PCT: Procalcitonin; ALB: Albumin.

Table 2 Values assigned to each factor

Variable	Assignment
Age	Value
History of diabetes	1 = occurred; 0 = did not occur
APACHE II rating	Value
CTSI score	Value
CRP	Value
PCT	Value
ALB	Value
Grouping	1 = occurred; 0 = did not occur

APACHE: Acute Physiology and Chronic Health Evaluation; CTSI: Computed tomography severity index; CRP: C-reactive protein; PCT: Procalcitonin; ALB: Albumin.

Table 3 Logistic regression analysis of factors influencing postoperative infection recurrence

Variable	B	SE	Wald	P value	Exp (B)	95% confidence interval of Exp (B)
						Lower limit	Upper limit
APACHE II rating	0.325	0.096	11.512	0.001	1.384	1.147	1.670
CTSI score	1.442	0.303	22.648	< 0.001	4.231	2.336	7.663
CRP	0.049	0.014	12.969	< 0.001	1.051	1.023	1.079
Constant	-16.847	3.077	29.973	< 0.001	< 0.001

APACHE: Acute Physiology and Chronic Health Evaluation; CTSI: Computed tomography severity index; CRP: C-reactive protein.