Comparison between interrupted closure technique and traditional closure technique in endoscopic full-thickness resection for treating gastric subepithelial lesions

Table 1 Baseline characteristics of patients and resected lesions, n (%)

	Experimental group (n = 44)	Control group (n = 46)	P value
Age [M, (Q1, Q3), years]	56.5 (49.0, 64.5)	58.5 (49.0, 62.0)	0.994
Sex			0.411
Male	21 (47.73)	18 (39.13)
Female	23 (52.27)	28 (60.87)
Maximum lesion diameter [M, (Q1, Q3), mm]	29.5 (20.0, 39.0)	29.5 (20.0, 48.0)	0.474
Lesion location			0.296
Fundus of stomach	18 (40.90)	26 (56.52)
Gastric body	23 (52.27)	18 (39.13)
Antrum of stomach	3 (6.82)	2 (4.35)
Level of origin of lesion			0.072
Not reaching muscularis propria	3 (6.82)	0 (0)
Muscularis propria	41 (93.18)	46 (100)
Growth pattern			0.875
Intraluminal growth	3 (6.82)	3 (6.52)
Extraluminal growth	2 (4.54)	1 (2.17)
Intraluminal and extraluminal growth	39 (88.64)	42 (91.30)
Pathological type			0.634
Stromal tumor	25 (56.82)	33 (71.74)
Leiomyoma	10 (22.73)	6 (13.04)
Ectopia pancreas	2 (4.54)	1 (2.17)
Neurofibroma	3 (6.82)	2 (4.35)
Other	3 (6.82)	4 (8.70)

M: Median.

Table 2 Comparison of intraoperative characteristics between the two groups, n (%)

	Experimental group (n = 44)	Control group (n = 46)	P value
Complete wound closure			> 0.999
Yes	44 (100)	46 (100)
No	0 (0)	0 (0)
En bloc resection			> 0.999
Yes	44 (100)	46 (100)
No	0 (0)	0 (0)
Intraoperative bleeding			> 0.999
Yes	0 (0)	0 (0)
No	44 (100)	46 (100)
Gas complication
Subcutaneous emphysema	0 (0)	0 (0)	> 0.999
Pneumomediastinum	0 (0)	0 (0)	> 0.999
Severe pneumothorax	0 (0)	0 (0)	> 0.999
Severe pneumoperitoneum	1 (2.27)	12 (26.09)	0.001
Operative time [M, (Q1, Q3), minute]	29.5 (20.0, 39.0)	29.5 (20.0, 48.0)	0.474
Intraoperative traction			0.673
Yes	8 (18.18)	10 (21.74)
No	36 (81.82)	36 (78.26)
Complete lesion removal			0.975
Yes	43 (97.73)	45 (97.83)
No	1 (2.27)	1 (2.17)

M: Median.

Table 3 Comparison of postoperative characteristics between the two groups, n (%)

	Experimental group (n = 44)	Control group (n = 46)	P value
Postoperative CRP [M, (Q1, Q3), mg/L]	17.98 (7.3, 34.2)	30.8 (16.1, 47.1)	0.066
Postoperative white blood cell count [M, (Q1, Q3), 109/L]	8.9 (7.9, 11.2)	10.6 (9.0, 13.0)	0.069
Postoperative neutrophil percentage [M, (Q1, Q3), %]	81.7 (75.7, 84.9)	82.4 (76.7, 84.7)	0.577
Postoperative maximum body temperature [M, (Q1, Q3), °C]	36.8 (36.7, 36.9)	36.8 (36.8, 37.5)	0.149
NRS 1 day postoperative [M, (Q1, Q3), points]	3 (2, 3.6)	4 (3, 5)	< 0.001
NRS 4 days postoperative [M, (Q1, Q3), points]	1 (1, 2.0)	2 (1, 2.3)	< 0.001
Delayed postoperative bleeding			> 0.999
Yes	0 (0)	0 (0)
No	44 (100)	46 (100)
Delayed postoperative perforation			> 0.999
Yes	0 (0)	0 (0)
No	44 (100)	46 (100)
Postoperative infection			0.008
Yes	7 (15.91)	19 (41.30)
No	37 (84.09)	27 (58.70)
The days of use antibiotic [M, (Q1, Q3), day]	3.5 (1.3, 5)	5 (3.8, 6)	0.013
Postoperative hospital stays [M, (Q1, Q3), day]	6 (5, 7)	6 (5, 7)	0.314
Total hospitalization costs [M, (Q1, Q3), CNY]	19843.3 (18361.6, 22260.5)	20862.5 (19475.0, 24398.3)	0.075

M: Median; CNY: China yuan; CRP: C-reactive protein; NRS: Numerical rating scale.