Clinical characteristics and transabdominal ultrasound features that associated with T3-T4 staging in gastric cancer: A retrospective study

Table 1 Patients characteristics and lesion profiles (n = 113)

Characteristics	N = 113
Age (years)	57.3 ± 11.9
BMI (kg/m2)	21.2 ± 3.2
Gender, n (%)
Male/female	71 (62.8)/42 (37.2)
Lesion thickness (cm)	1.5 ± 0.6
Lesion length (cm)	5.2 ± 2.3
Presence of angle sign, n (%)
Yes/no	89 (78.7)/24 (21.3)
Presence of ulcer, n (%)
Yes/no	63 (55.7)/50 (44.3)
Lesion location, n (%)
Gastric antrum	53 (46.9)
Gastric fundus	12 (10.6)
Gastric body	33 (29.3)
Gastric fundus + body	11 (9.7)
Gastric angle	4 (3.5)
Clinical feature, n (%)
Epigastrium discomfort or dull pain	36 (31.9)
Abdominal pain with black stool	18 (15.9)
Abdominal pain with belching	22 (19.5)
Abdominal distension with anorexia	17 (15.0)
Abdominal pain with vomiting	15 (13.3)
Dysphagia	5 (4.4)
CEA, n (%)
< 5 μg/L/≥ 5 μg/L	79 (69.9)/34 (30.1)
CA19-9, n (%)
< 37 kU/L/≥ 37 kU/L	85 (75.2)/28 (24.8)
Pathological type, n (%)
Adenocarcinoma	113 (100.0)
Histologic type, n (%)
Poor differentiated	71 (62.8)
Moderate differentiated	37 (32.8)
Well differentiated	5 (4.4)
Lauren type, n (%)
Diffuse type	70 (61.9)
Hybrid type	15 (13.3)
Intestinal type	28 (24.8)

BMI: Body mass index; CEA: Carcinoembryonic antigen.

Table 2 Univariate analysis of influence factors between pathological T1-T2 staging and T3-T4 staging

Variable	T3-T4 staging (n = 92)	T1-T2 staging (n = 21)	t/χ2	P value
Age (years)	58.4 ± 12.2	57.7 ± 10.9	-0.250	0.803
BMI (kg/m2)	21.4 ± 3.2	20.1 ± 2.9	-1.862	0.065
Gender
Male/female	61/31	10/11	2.556	0.110
Lesion thickness (cm)	1.6 ± 0.6	1.0 ± 0.4	-4.022	< 0.001
Lesion length (cm)	5.7 ± 2.2	2.9 ± 1.0	-5.596	< 0.001
Presence of angle sign
Yes/no	85/7	4/17	50.684	< 0.001
Presence of ulcer
Yes/no	52/40	11/10	0.119	0.730
Lesion location
Gastric antrum	44	9	7.740	0.102
Gastric fundus	9	3
Gastric body	30	3
Gastric fundus + body	6	5
Gastric angle	3	1
CEA	58/34	21/0		< 0.001
< 5 μg/L/≥ 5 μg/L
CA19-9	67/25	18/3	0.911	0.034
< 37 kU/L/≥ 37 kU/L
Clinical feature
Epigastrium discomfort or dull pain	29	7		0.758
Abdominal pain with black stool	15	3
Abdominal pain with belching	17	5
Abdominal distension with anorexia	15	2
Abdominal pain with vomiting	13	2
Dysphagia	3	2
Histologic type
Poor differentiated	60	11	2.190	0.335
Moderate differentiated	29	8
Well differentiated	3	2
Lauren type
Diffuse type	60	10	2.579	0.275
Hybrid type	12	3
Intestinal type	20	8

BMI: Body mass index; CEA: Carcinoembryonic antigen.

Table 3 Multivariate analysis of influence factors between pathological T1-T2 staging and T3-T4 staging

	B	SE	P value	OR	95%CI
Lesion thickness (cm)	-	-	0.933	-	-
Lesion length (cm)	0.864	0.315	0.006	2.373	1.281-4.396
Angle sign (yes/no)	3.437	0.992	< 0.001	31.083	4.449-217.164
CA19-9 (< 37 kU/L/≥ 37 kU/L)	-	-	0.308	-	-
CEA (< 5 μg/L/≥ 5 μg/L)	-	-	0.997	-	-

OR: Odds ratio; 95%CI: 95% confidence interval.