Nutritional and inflammatory indicators differ among patients with colorectal cancer with distinct microsatellite stability statuses

Table 1 Definitions of some specific terms, n (%)

Clinical indicators	MSI (n = 28)	MSS (n = 28)	P value
Gender			1.000
Male	15 (53.57)	15 (53.57)
Female	13 (46.43)	13 (46.43)
Age, years	67.39 ± 12.470	63.75 ± 11.407	0.259
Tumor size			0.010
≥ 5 cm	18 (64.29)	6 (21.43)
< 5 cm	10 (35.71)	22 (78.57)
Lymph node metastases			0.008
Degree of differentiation			0.412
Stage			0.019
≤ stage II	21 (75.00)	6 (21.43)
> stage II	7 (25.00)	22 (78.57)

MSI: Microsatellite instability; MSS: Microsatellite stability.

Table 2 Analysis of nutritional indices, mean (range)

Nutritional indices	MSI (n = 28)	MSS (n = 28)	P value
Fasting blood glucose	5.93 (3.95-11.77)	6.38 (4.66-9.91)	0.330
Triglyceride	1.16 (0.40-3.29)	1.14 (0.39-2.40)	0.851
Serum cholesterol	4.19 (2.64-5.86)	4.69 (2.95-7.09)	0.054
Serum albumin	33.95 (24.86-48.50)	38.92 (23.70-47.22)	0.002
BMI	22.15 (14.22-29.07)	24.80 (17.75-31.89)	0.011

MSI: Microsatellite instability; MSS: Microsatellite stability; BMI: Body mass index.

Table 3 Analysis of inflammatory indices, mean (range)

Inflammatory indices	MSI (n = 28)	MSS (n = 28)	P value
Neutrophil count	4.89 (1.45-12.01)	3.92 (2.01-6.07)	0.065
Lymphocyte count	1.37 (0.65-2.19)	1.66 (0.74-2.80)	0.020
Monocyte count	0.46 (0.21-0.82)	0.41 (0.22-0.81)	0.152
NLR	3.88 (1.24-13.05)	2.57 (1.00-4.74)	0.014
LMR	3.48 (1.20-8.76)	4.24 (2.14-7.36)	0.097

MSI: Microsatellite instability; MSS: Microsatellite stability; NLR: Neutrophil-to-lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio.

Table 4 Analysis of tumor markers, mean (range)

Tumor markers	MSI (n = 28)	MSS (n = 28)	P value
Preoperative CEA	25.57 (0.49-577.52)	17.06 (1.00-170.22)	0.695
Preoperative CA19-9	35.58 (2.00-439.00)	60.20 (5.02-870)	0.475

MSI: Microsatellite instability; MSS: Microsatellite stability; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9.