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©The Author(s) 2025.
World J Gastrointest Surg. Apr 27, 2025; 17(4): 101295
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.101295
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.101295
Table 1 The general clinical data of the three groups of patients were compared
Modified pancreatic duct stent drainage group (n = 59) | Nasobiliary drainage group (n = 58) | Standard biliary drainage group | χ2/F value | P value | |
Gender (male/female) | 35 (59.32)/24 (40.68) | 33 (56.90)/25 (43.10) | 32 (55.17)/26 (44.83) | 0.208 | 0.901 |
ASA classification (I/II/III) | 22 (37.29)/28 (47.46)/9 (15.25) | 11 (18.97)/36 (62.07)/11 (18.97) | 16 (27.59)/32 (54.24)/10 (17.24) | 4.887 | 0.299 |
The number of gallstones in the bile duct (1/2/3/≥ 4) | 29 (49.15)/7 (11.86)/5 (8.47)/18 (30.51) | 28 (48.28)/5 (8.62)/5 (8.62)/20 (34.48) | 23 (39.66)/6 (10.34)/5 (8.62)/24 (41.38) | 2 | 0.92 |
Age (year) | 51.42 ± 15.14 | 52.00 ± 16.08 | 51.84 ± 15.84 | 0.021 | 0.979 |
BMI (kg/m2) | 23.34 ± 3.82 | 23.29 ± 3.67 | 23.16 ± 3.54 | 0.037 | 0.964 |
History of drinking (yes/no) | 26 (44.07)/33 (55.93) | 24 (41.38)/34 (58.62) | 23 (39.66)/35 (60.34) | 0.238 | 0.888 |
Time of onset before surgery (hours) | 35.51 ± 3.25 | 35.94 ± 3.58 | 36.10 ± 4.33 | 0.389 | 0.678 |
Total hospital stay duration (days) | 9.12 ± 4.34 | 10.62 ± 5.06 | 11.04 ± 5.13 | 2.536 | 0.082 |
Disease duration (month) | 21.14 ± 4.28 | 22.04 ± 4.05 | 21.67 ± 3.94 | 0.715 | 0.491 |
Surgical duration (minutes) | 61.04 ± 8.91 | 60.55 ± 6.42 | 60.07 ± 7.49 | 0.233 | 0.792 |
Diameter of the bile duct (cm) | 1.34 ± 0.43 | 1.31 ± 0.48 | 1.38 ± 0.51 | 0.318 | 0.728 |
Stone diameter (cm) | 0.86 ± 0.35 | 0.88 ± 0.36 | 0.91 ± 0.43 | 0.254 | 0.776 |
Table 2 Comparison of laboratory indicators among three groups of patients, mean ± SD
Modified pancreatic duct stent drainage group (n = 59) | Nasobiliary drainage group (n = 58) | Standard biliary drainage group | F value | P value | P1 value | P2 value | P3 value | |
AST (U/L) | ||||||||
24 hours before the surgery | 58.38 ± 18.49 | 55.71 ± 20.07 | 55.75 ± 20.84 | 0.217 | 0.642 | |||
24 hours after the surgery | 29.28 ± 3.47 | 48.64 ± 4.37 | 30.13 ± 3.88 | 449.671 | < 0.001 | < 0.001 | < 0.001 | 0.240 |
ALT (U/L) | ||||||||
24 hours before the surgery | 85.36 ± 6.41 | 83.15 ± 6.74 | 84.28 ± 6.69 | 0.221 | 0.639 | |||
24 hours after the surgery | 35.44 ± 4.73 | 68.54 ± 5.58 | 36.49 ± 6.33 | 650.159 | < 0.001 | < 0.001 | < 0.001 | 0.294 |
ALP (U/L) | ||||||||
24 hours before the surgery | 160.42 ± 35.48 | 159.45 ± 34.82 | 158.47 ± 31.82 | 1.153 | 0.284 | |||
24 hours after the surgery | 133.09 ± 33.21 | 153.14 ± 36.58 | 134.54 ± 31.25 | 6.390 | 0.002 | 0.002 | 0.003 | 0.837 |
GGT (U/L) | ||||||||
24 hours before the surgery | 383.45 ± 106.82 | 364.58 ± 119.42 | 322.84 ± 128.94 | 0.402 | 0.527 | |||
24 hours after the surgery | 252.64 ± 44.52 | 294.59 ± 51.60 | 255.52 ± 55.31 | 12.314 | < 0.001 | < 0.001 | < 0.001 | 0.668 |
TBIL (mol/L) | ||||||||
24 hours before the surgery | 28.65 ± 6.77 | 28.94 ± 6.82 | 28.59 ± 5.82 | 1.603 | 0.207 | |||
24 hours after the surgery | 16.08 ± 3.38 | 24.36 ± 4.16 | 16.18 ± 3.67 | 94.115 | < 0.001 | < 0.001 | < 0.001 | 0.878 |
DBIL (mol/L) | ||||||||
24 hours before the surgery | 12.53 ± 3.56 | 13.05 ± 3.81 | 13.34 ± 3.64 | 3.165 | 0.077 | |||
24 hours after the surgery | 8.59 ± 2.14 | 9.93 ± 2.42 | 8.96 ± 2.57 | 5.213 | 0.006 | 0.002 | 0.032 | 0.328 |
CRP (mg/L) | ||||||||
24 hours before the surgery | 104.58 ± 5.89 | 102.57 ± 6.68 | 101.53 ± 5.46 | 2.516 | 0.115 | |||
24 hours after the surgery | 83.65 ± 6.91 | 96.08 ± 7.04 | 84.53 ± 6.31 | 62.572 | < 0.001 | < 0.001 | < 0.001 | 0.311 |
WBC (× 109/L) | ||||||||
24 hours before the surgery | 11.28 ± 5.94 | 10.64 ± 4.58 | 10.53 ± 5.08 | 0.089 | 0.766 | |||
24 hours after the surgery | 9.51 ± 4.41 | 9.46 ± 5.02 | 9.48 ± 4.66 | 0.003 | 0.997 | 0.942 | 0.984 | 0.959 |
Hb (g/L) | ||||||||
24 hours before the surgery | 133.54 ± 20.19 | 134.48 ± 20.25 | 134.82 ± 20.72 | 2.171 | 0.143 | |||
24 hours after the surgery | 123.14 ± 19.58 | 124.15 ± 18.24 | 123.31 ± 18.94 | 0.043 | 0.958 | 0.796 | 0.805 | 0.992 |
NEU (%) | ||||||||
24 hours before the surgery | 0.78 ± 0.14 | 0.79 ± 0.13 | 0.78 ± 0.15 | 0.627 | 0.430 | |||
24 hours after the surgery | 0.73 ± 0.08 | 0.76 ± 0.09 | 0.74 ± 0.07 | 1.337 | 0.265 | 0.157 | 0.159 | 0.999 |
AMY (IU/L) | ||||||||
24 hours before the surgery | 281.26 ± 94.15 | 274.59 ± 93.08 | 268.42 ± 99.81 | 1.116 | 0.292 | |||
24 hours after the surgery | 121.46 ± 44.28 | 175.83 ± 46.82 | 127.43 ± 41.08 | 26.653 | < 0.001 | < 0.001 | < 0.001 | 0.432 |
Table 3 Comparison of visual analogue scale scores among the three groups of patients, mean ± SD
Modified pancreatic duct stent drainage group (n = 59) | Nasobiliary drainage group (n = 58) | Standard biliary drainage group (n = 58) | F value | P value | P1 value | P2 value | P3 value | |
VAS (point) | ||||||||
24 hours before the surgery | 6.25 ± 2.16 | 6.24 ± 2.45 | 6.26 ± 2.54 | 0.077 | 0.781 | |||
24 hours after the surgery | 4.36 ± 1.18 | 5.54 ± 1.24 | 4.92 ± 1.68 | 10.416 | < 0.001 | < 0.001 | 0.017 | 0.033 |
Table 4 Comparison of complication occurrence in three groups of patients
Modified pancreatic duct stent drainage group (n = 59) | Nasobiliary drainage group (n = 58) | Standard biliary drainage group (n = 58) | χ2 value | P value | |
Complications | 14 (23.73) | 18 (31.03) | 21 (36.21) | 2.180 | 0.336 |
Pancreatitis | 1 (1.69) | 0 (0.00) | 0 (0.00) | ||
Cholangitis | 0 (0.00) | 1 (1.72) | 0 (0.00) | ||
Hemorrhage | 0 (0.00) | 2 (3.45) | 2 (3.45) | ||
Perforation | 1 (1.69) | 0 (0.00) | 1 (1.72) | ||
Wound infection | 0 (0.00) | 0 (0.00) | 1 (1.72) | ||
Hyperamylasemia | 12 (20.34) | 15 (25.86) | 17 (29.31) | ||
Death | 0 (0.00) | 0 (0.00) | 0 (0.00) |
- Citation: Qian LJ, Xu C, Wang JR, Quan J. Efficacy of modified pancreatic duct stent drainage during endoscopic retrograde cholangiopancreatography for common bile duct stones. World J Gastrointest Surg 2025; 17(4): 101295
- URL: https://www.wjgnet.com/1948-9366/full/v17/i4/101295.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v17.i4.101295