Copyright
©The Author(s) 2024.
World J Gastrointest Surg. Sep 27, 2024; 16(9): 2942-2952
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2942
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2942
| Low-risk group (n = 80) | High-risk group (n = 52) | P value |
Age (years) | 58.2 ± 13.1 | 68.6 ± 10.0 | < 0.001 |
Gender | 0.482 | ||
Female | 44 (55.0) | 24 (46.2) | |
Male | 36 (45.0) | 28 (53.8) | |
Maximal longitudinal diameter (cm) | 5.8 ± 2.5 | 10.2 ± 2.8 | < 0.001 |
The position of the tumor | 0.270 | ||
Stomach | 48 (60.0) | 24 (46.2) | |
Gastric extracorporeal | 32 (40.0) | 28 (53.8) | |
Mitotic figures in pathology (50/HPF) | < 0.001 | ||
≤ 5 | 72 (90.0) | 10 (23.8) | |
> 5 | 8 (10.0) | 42 (76.2) |
Sequence screening | Imaging omics features |
DWI (3) | [['original_shape_Sphericity'] |
'wavelet-HHH_glszm_ZoneEntropy'] | |
['wavelet-LHH_firstorder_Kurtosis'] | |
T1WI + CE-T1WI fs (5) | [['lbp-3D-k_firstorder_Minimum'] |
['lbp-3D-m2_firstorder_Mean'] | |
['wavelet-HHL_glcm_ClusterShade'] | |
['wavelet-HLL_firstorder_Skewness'] | |
['wavelet-LHH_glszm_SizeZoneNonUniformityNormalized'] | |
T1WI + T2WI + DWI +; CE-T1WI fs (5) | ['wavelet-HHL_firstorder_Skewness'] |
['wavelet-HLL_firstorder_Skewness'] | |
['wavelet-HLL_firstorder_Kurtosis'] | |
['original_shape_Maximum2DDiameterSlice'] | |
['wavelet-LHL_firstorder_Skewness'] |
| Test group | Training group | ||||
AUC (95%CI) | Sensitivity (%) | Specificity (%) | AUC (95%CI) | Sensitivity (%) | Specificity (%) | |
DWI | 0.960 (0.840-1.000) | 80.0 | 100.0 | 0.889 (0.736-1.000) | 88.9 | 66.7 |
T1WI | 0.812 (0.467-1.000) | 75.0 | 100.0 | 0.864 (0.677-1.000) | 66.7 | 100.0 |
T2WI fs | 0.710 (0.495-0.894) | 60.0 | 60.0 | 0.828 (0.727-0.917) | 82.6 | 65.2 |
| Test group | Training group | ||||
AUC (95%CI) | Sensitivity (%) | Specificity (%) | AUC (95%CI) | Sensitivity (%) | Specificity (%) | |
TIWI + CE-T1WI fs | 0.834 (0.736-0.922) | 70.4 | 85.2 | 0.917 (0.825-0.984) | 77.8 | 88.9 |
T2WIfs + CE-T1WI fs | 0.783 (0.661-0.893) | 73.9 | 73.0 | 0.866 (0.769-0.949) | 73.9 | 91.3 |
DWI + CE-T1WI fs | 0.796 (0.684-0.899) | 70.4 | 77.8 | 0.825 (0.714-0.917) | 70.8 | 79.2 |
T1WI + T2WIfs + DWI + CE-T1WI fs | 0.818 (0.727-0.897) | 60.0 | 77.1 | 0.770 (0.567-0.938) | 70.0 | 80.0 |
- Citation: Pan GH, Zhou F, Chen WB, Pan ZJ. Advancing gastrointestinal stromal tumor management: The role of imagomics features in precision risk assessment. World J Gastrointest Surg 2024; 16(9): 2942-2952
- URL: https://www.wjgnet.com/1948-9366/full/v16/i9/2942.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v16.i9.2942