Systemic immune-inflammation index combined with pediatric appendicitis score in assessing the severity and prognosis for paediatric appendicitis

Table 1 Comparison of demographic characteristics between acute appendicitis and chronic appendicitis groups

Demographic characteristic	Acute appendicitis group (n = 51)	Chronic appendicitis group (n = 53)	t value	P value
Age (years)	9.75 ± 2.14	9.48 ± 2.05	0.654	0.515
Gender (male/female), n (%)	26 (50.98)/25 (49.02)	29 (54.72)/24 (45.28)	0.034	0.853
BMI (kg/m2)	18.52 ± 3.21	18.76 ± 3.45	0.367	0.714
Duration of symptoms (days)	2.61 ± 1.73	30.15 ± 2.66	62.809	< 0.001
Mode of delivery, n (%)
Vaginal delivery, n (%)	29 (56.86)	29 (54.72)	0.001	0.982
Cesarean section, n (%)	22 (43.14)	24 (45.28)

Table 2 Systemic immune-inflammation index comparison between acute appendicitis and chronic appendicitis groups

Parameter	Acute appendicitis group (n = 51)	Chronic appendicitis group (n = 53)	t value	P value
Neutrophil count (× 109/L)	7.82 ± 2.03	6.76 ± 1.87	2.754	0.007
Lymphocyte count (× 109/L)	2.54 ± 0.87	3.11 ± 0.92	3.233	0.002
Platelet count (× 109/L)	290.62 ± 45.91	271.34 ± 47.68	2.101	0.038
SII	660.41 ± 80.34	605.27 ± 78.25	3.544	< 0.001

SII: Systemic immune-inflammation index.

Table 3 Pediatric appendicitis score comparison between acute appendicitis and chronic appendicitis groups

Parameter	Acute appendicitis group (n = 51)	Chronic appendicitis group (n = 53)	t value	P value
Alvarado score	7.13 ± 1.72	7.98 ± 1.85	2.427	0.017
AIR score	5.05 ± 2.01	5.91 ± 2.15	2.104	0.038
Imaging findings score	2.07 ± 0.94	2.65 ± 1.01	3.032	0.003
PAS	14.32 ± 3.45	17.71 ± 3.59	4.925	< 0.001

PAS: Pediatric appendicitis score.

Table 4 Correlation analysis of the systemic immune-inflammation index, pediatric appendicitis score, and disease severity in children aged 5 years and older with appendicitis

Parameter	r	R2	P value
Neutrophil count (× 109/L)	-0.263	0.069	0.007
Lymphocyte count (× 109/L)	0.305	0.093	0.002
Platelet count (× 109/L)	-0.204	0.041	0.038
SII	-0.331	0.11	< 0.001
Alvarado score	0.233	0.054	0.017
AIR score	0.204	0.042	0.038
Imaging findings score	0.287	0.082	0.003
PAS	0.438	0.192	< 0.001

SII: Systemic immune-inflammation index; PAS: Pediatric appendicitis score.