Peritoneal fluid indocyanine green test for diagnosis of gut leakage in anastomotic leakage rats and colorectal surgery patients

Table 1 Characteristics of six patients with enterostomy stomas

Patients	n = 6
Age (yr), mean ± SD	66.3 ± 10.6
Gender (male/female)	2/4
Diagnose	6 (100%)
Rectal cancer
Surgery approach	6 (100%)
Laparoscopic rectal cancer resection plus ileostomy

Table 2 Patient characteristics in the diagnostic test

Characteristic	Value (n = 17) (percentage)
Age (yr), mean ± SD	58.6 ± 11.4
Gender (male/female)	10/7
Diagnosis, n (%)
Ascending colon cancer	3 (17.6)
Descending colon cancer	2 (11.8)
Sigmoid colon cancer	4 (23.5)
Rectal cancer	8 (47.1)
Surgery, n (%)
Laparoscopic right hemicolectomy	3 (17.6)
Laparoscopic left hemicolectomy	2 (11.8)
Laparoscopic sigmoidectomy	4 (23.5)
Laparoscopic rectal cancer resection	8 (47.1)
Enrollment criteria
Feces or pus discharged from drainage tube, n (%)	2 (11.8)
Peritonitis with leukocytosis, n (%)	5 (29.4)
Peritonitis with procalcitonin, n (%)	5 (29.4)
Peritonitis with C-reactive protein, n (%)	3 (17.6)
Abnormal drainage volume (> 100 mL lasting 3 d), n (%)	2 (11.8)
Postoperative fever (> 38°C), n (%)	7 (41.2)
Intraoperative blood loss > 50 mL, n (%)	3 (17.6)
Operative time > 3 h, n (%)	6 (35.3)
Tachycardia POD 1 (≥ 100 bpm), n (%)	2 (11.8)
Clinical T stage (T3/T4)	7/3

Table 3 Contingency table evaluating the accuracy of indocyanine green measurement for the diagnosis of postoperative gut leakage

ICG test	Postoperative gut leakage		Total
	Positive	Negative
Positive	5	2	7
Negative	0	10	10
Total	5	12	17

ICG: Indocyanine green.