Correlation of serum albumin level on postoperative day 2 with hospital length of stay in patients undergoing emergency surgery for perforated peptic ulcer

Table 1 Main clinical data and results of blood routine and albumin in the two groups of patients, n (%)

	≤ 7-d group (n = 8)	> 7-d group (n = 29)	P value
Age	54.38 ± 27.25	59.31 ± 18.433	0.551b
Sex			0.332c
Female	3 (37.5)	5 (17.2)
Male	5 (62.5)	24 (82.8)
Perforation site			1c
Stomach	7 (87.5)	26 (89.7)
Duodenum	1 (12.5)	3 (10.3)
Treatment time	47 (1, 720)	47 (1, 168)	0.67a
Surgical approach			0.811c
Open abdomen	3 (37.5)	14 (48.3)
Laparoscopy	5 (62.5)	13 (44.8)
Laparoscopic laparotomy	0	2 (6.9)
Piercing Diameter (cm)	0.9 ± 0.5	1 (0.5, 1.1)	0.718a
Operation time (min)	94 ± 22	120 (82, 145)	0.133a
Empyema			0.701c
Little-medium	3 (37.5)	14 (48.3)
Many - a lot	5 (62.5)	15 (51.7)
ICU length of stay (d)	1.8 ± 1.5	1 (0.6, 2.5)	0.763a
Lung infection	4 (50)	13 (44.8)	1c
Pleural effusion	1 (12.5)	7 (24.1)	0.655c
Localized ascites	1 (12.5)	4 (13.8)	1c
Preoperative leukocytes (× 109/L)	13.94 ± 5.22	12.32 ± 5.52	0.463b
Preoperative centriocytes (× 109/L)	12.43 (6.47, 16.89)	10.55 ± 5.26	0.483a
Preoperative lymphocytes (× 109/L)	0.86 ± 0.46	1.17 ± 0.73	0.255b
Preoperative platelets (×109/L)	268 ± 135	230 (197, 315)	0.543a
Preoperative N/LR	18.07 ± 10.84	8.51 (5.8, 17.57)	0.097a
Preoperative P/LR	497.20 ± 515.11	303.08 ± 198.75	0.328b
Albumin (preoperative, g/L) (n, mean ± SD)	7 (39.3 ± 6.3)	28 (39.9 ± 5.1)	0.778b
Albumin (D1, g/L) (n, mean ± SD)	6 (32.2 ± 5.1)	20 (30.6 ± 3.4)	0.379b
Albumin (D2, g/L) (n, mean ± SD)	7 (37.7 ± 3.7)	23 (32.6 ± 3.3)	0.009b
Albumin (D3, g/L) (n, mean ± SD)	4 (38.6 ± 6.1)	24 (33.6 ± 2.8)	0.201b

^aMann-Whienty U test.

^bt test.

^cFisher's exact test.

ICU: Intensive care unit; D1: Postoperative day 1; D2: Postoperative day 2; D3: Postoperative day 3; P/LR: Platelet/lymphocyte ratio; N/LR: Neutrophil/lymphocyte ratio.

Table 2 Multivariate analysis of hospital stay ≤ 7 d

	Regression coefficient B	SE	Relative risk	95%CI	P value
Albumin (D2)	-0.429	0.202	1.535	1.033-2.283	0.034
Preoperative N/LR	-0.029	0.068	1.029	0.901-1.175	0.673

D2: Postoperative day 2; N/LR: Neutrophil/lymphocyte ratio; CI: Confidence interval.

Table 3 Multivariate analysis of hospital stay > 7 d

	Regression coefficients B	SE	Relative risk	95%CI	P value
Albumin (D2)	0.429	0.202	0.651	0.438-0.968	0.034
Preoperative N/LR	0.029	0.068	0.972	0.851-1.11	0.673

D2: Postoperative day 2; N/LR: Neutrophil/lymphocyte ratio; CI: Confidence interval.