From advanced diagnosis to advanced resection in early neoplastic colorectal lesions: Never-ending and trending topics in the 2020s

Table 1 Indications for colon and rectum endoscopic submucosal dissection[95-100]

	Europe	United States	Japan
Colon and rectum	Lesions > 20 mm with high suspicion of limited submucosal invasion:	Submucosally invasive cancer	LST-NG, pseudo-depressed1
			Vi-type pit pattern lesions1
			Carcinoma with shallow T1 (SM) invasion1
		Type V Kudo pit pattern
			Large depressed-type tumors1
		Paris 0-IIc	Large protruded-type lesions suspected to be carcinoma1
	Paris 0–IIa+c or 0–III	Paris (0-Is or 0-IIa+Is)
	Nongranular surface	Rectosigmoid location	Mucosal tumors with submucosal fibrosis
	Advanced surface pattern	Nongranular LST ≥ 20 mm
			Sporadic tumors in IBD
		Granular LST ≥ 30 mm
			Local residual/recurrent early carcinomas
		Residual/recurrent adenomas
	Residual/recurrent lesions

¹Not amenable to en bloc resection by endoscopic mucosal resection. IBD: Inflammatory bowel disease; LST: Laterally spreading tumor; NG: Nongranular; SM: Submucosal.