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©The Author(s) 2022.
World J Gastrointest Surg. May 27, 2022; 14(5): 383-396
Published online May 27, 2022. doi: 10.4240/wjgs.v14.i5.383
Published online May 27, 2022. doi: 10.4240/wjgs.v14.i5.383
Table 1 The 5th classification system of World Health Organization for gastroenteropancreatic neuroendocrine neoplasms (2019)[10]
| Classification | Differentiation status | Ki-67 index | Mitotic rate |
| Grade 1, NET | Well differentiated | < 3% | < 2 |
| Grade 2, NET | Well differentiated | 3% to 20% | 2 to 20 |
| Grade 3, NET | Well differentiated | > 20% | > 20 |
| Small cell type, NEC | Poorly differentiated | > 20% | > 20 |
| Large cell type, NEC | Poorly differentiated | > 20% | > 20 |
| Mixed NEN | Well or poorlydifferentiated | Variable | Variable |
- Citation: Dai M, Mullins CS, Lu L, Alsfasser G, Linnebacher M. Recent advances in diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms. World J Gastrointest Surg 2022; 14(5): 383-396
- URL: https://www.wjgnet.com/1948-9366/full/v14/i5/383.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v14.i5.383