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©The Author(s) 2022.
World J Gastrointest Surg. Feb 27, 2022; 14(2): 174-184
Published online Feb 27, 2022. doi: 10.4240/wjgs.v14.i2.174
Published online Feb 27, 2022. doi: 10.4240/wjgs.v14.i2.174
Table 1 Characteristics of the study cohort stratified by surgical method
| Total (n = 166) | CM (n = 133) | PPM (n = 33) | P value | ||
| Female, n (%) | 129 (77.7) | 106 (77.4) | 23 (69.7) | 0.16 | |
| Age (yr), median (range) | 32.5 (10-68) | 32.0 (10-68) | 33 (13-51) | 0.85 | |
| Symptoms, n (%) | |||||
| Accidentally found | 104 (62.7) | 83 (62.4) | 21 (63.6) | 0.84 | |
| Abdominal pain | 53 (31.9) | 43 (32.3) | 10 (30.3) | 0.75 | |
| Abdominal distension | 6 (3.6) | 5 (3.8) | 1 (3.0) | 0.8 | |
| Nausea and vomiting | 2 (1.2) | 1 (0.8) | 1 (3.0) | 0.49 | |
| Jaundice | 1 (0.6) | 1 (0.8) | 0 (0) | 0.32 | |
| Hospital stay (d) ± SD | 12.53 ± 6.87 | 12.35 ± 6.21 | 13.3 ± 9.14 | 0.49 | |
| Total expense (yuan) ± SD | 46248 ± 25414 | 44213 ± 20487 | 54084 ± 38551 | 0.21 | |
Table 2 Intraoperative index and pathological outcomes of the study cohort stratified by surgical method
| Total (n = 166) | CM (n = 133) | PPM (n = 33) | P value | |
| Intraoperative index | ||||
| Surgical approach, n (%) | 0.126 | |||
| laparotomy | 139 (80.1) | 108 (81.2) | 31 (93.9) | |
| laparoscopic | 13 (7.8) | 11 (8.3) | 2 (6.1) | |
| Robot | 14 (8.4) | 14 (10.5) | 0 (0) | |
| Surgeon experiences, mean (yr) | 19.3 | 19.0 | 19.5 | 0.85 |
| Operation duration, median (range) | 135 (27-381) | 135 (27-381) | 120 (50-301) | 0.71 |
| Intraoperative bleeding volume, median (± SD) | 200 (0-2000) | 200 (0-2000) | 100 (50-600) | 0.488 |
| Pathological outcomes | ||||
| Median size (mm), median (range) | 40 (3.5-140) | 45 (3.5-140) | 32 (17-140) | 0.069 |
| Tumor location, n (%) | 0.001a | |||
| Head | 69 (41.6) | 46 (34.6) | 23 (69.7) | |
| Body | 19 (11.4) | 15 (11.3) | 4 (12.1) | |
| Tail | 17 (10.2) | 17 (12.8) | 0 (0) | |
| Multiple sites | 64 (38.6) | 55 (41.4) | 6 (18.2) | |
| Ki67 index, n (%) | 0.53a | |||
| I | 141 (84.9) | 115 (86.5) | 26 (78.8) | |
| II | 22 (13.3) | 16 (12.0) | 6 (18.2) | |
| III | 3 (1.8) | 2 (1.5) | 1 (3.0) | |
| Peripheral tissue invasion, n (%) | 18 (10.8) | 15 (11.3) | 3 (9.1) | 0.426 |
| Positive margin status, n (%) | 12 (7.2) | 10 (7.5) | 2 (6.0) | 0.283 |
Table 3 Short-term and long-term outcomes of the study cohort stratified by surgical method
| Total (n = 166) | CM (n = 133) | PPM (n = 33) | P value | |
| Short-term complications | ||||
| Overall perioperative complication, n (%) | 33 (19.9) | 27 (20.3) | 6 (18.2) | 0.79 |
| Severe POPF | 6 (3.6) | 5 (3.8) | 1 (3.0) | 0.85 |
| delayed gastric emptying | 3 (1.8) | 3 (2.3) | 0 (0) | 0.56 |
| abdominal infection | 13 (7.8) | 12 (9.0) | 1 (3.0) | 0.43 |
| Bleeding | 5 (3.0) | 3 (2.3) | 2 (6.0) | 0.26 |
| Pancreatitis | 2 (1.2) | 2 (1.5) | 0 (0) | 0.49 |
| Multiple complications | 4 (2.4) | 2 (1.5) | 2 (6.0) | 0.18 |
| Severe perioperative complication, n (%) | 9 (5.4) | 7 (5.3) | 2 (6.0) | 1.0 |
| Long-term follow-up data | ||||
| Recurrence, n (%) | 6 (3.6) | 4 (3.0) | 2 (6.0) | 0.39 |
| Local | 4 (2.4) | 3 (2.3) | 1 (3.0) | |
| Distant | 2 (1.2) | 1 (0.8) | 1 (3.0) | |
| Alimentary stricture, n (%) | 6 (3.6) | 5 (3.7) | 1 (3.0) | 1.0 |
| Endocrine insufficiency, n (%) | 7 (4.2) | 6 (4.5) | 1 (3.0) | 1.0 |
| Exocrine insufficiency, n (%) | 30 (18.1) | 29 (21.8) | 1 (3.0) | 0.024 |
- Citation: Li YQ, Pan SB, Yan SS, Jin ZD, Huang HJ, Sun LQ. Impact of parenchyma-preserving surgical methods on treating patients with solid pseudopapillary neoplasms: A retrospective study with a large sample size. World J Gastrointest Surg 2022; 14(2): 174-184
- URL: https://www.wjgnet.com/1948-9366/full/v14/i2/174.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v14.i2.174