Copyright
©The Author(s) 2021.
World J Gastrointest Surg. Mar 27, 2021; 13(3): 256-266
Published online Mar 27, 2021. doi: 10.4240/wjgs.v13.i3.256
Published online Mar 27, 2021. doi: 10.4240/wjgs.v13.i3.256
Table 1 Baseline characteristics of sepsis patients
Baseline characteristic | n (%) |
Age, median (Q1, Q3) | 65 (59.71) |
Sex | |
Male | 145 (80.1) |
Female | 36 (19.9) |
BMI, mean (SD), kg/m2 | 23.5 (0.3) |
Tumor type | |
Gastric cancer | 91 (50.3) |
Colorectal cancer | 84 (46.4) |
Other abdominal tumors | 6 (3.3) |
Coexisting condition1 | |
Hypertension | 64 (35.4) |
Diabetes | 32 (17.7) |
Coronary heart disease | 17 (9.4) |
Chronic obstructive pulmonary disease | 11 (6.1) |
Arrhythmia | 9 (5.0) |
Chronic renal insufficiency | 2 (1.1) |
Location of infection2 | |
Abdominal infection | 134 (74.0) |
Enterogenous infection | 12 (6.6) |
Intrathoracic infection | 17 (9.4) |
Pulmonary infection | 31 (17.1) |
Skin and soft tissue infection | 6 (3.3) |
Surgical wound infection | 4 (2.2) |
Central line-associated bloodstream infection | 3 (1.7) |
Urinary tract infection | 2 (1.1) |
Length of first operation, median (Q1, Q3), min | 195 (140, 246) |
Table 2 Univariate analysis of sepsis patients
Parameter | n (%) | Survival rate at 90-d | P value |
Age, yr | 0.840 | ||
≤ 65 | 96 (53.0) | 0.885 | |
> 65 | 85 (47.0) | 0.894 | |
Sex | 0.254 | ||
Male | 145 (80.1) | 0.876 | |
Female | 36 (19.9) | 0.944 | |
BMI, kg/m2 | 0.028 | ||
≤ 20 | 37 (20.4) | 0.784 | |
20 < BMI ≤ 28 | 118 (65.2) | 0.932 | |
> 28 | 26 (14.4) | 0.846 | |
Length of first operation, min | 0.361 | ||
≤ 240 | 129 (71.3) | 0.876 | |
> 240 | 52 (28.7) | 0.923 | |
Empirical anti infection evaluation | 0.729 | ||
Sensitive | 132 (72.9) | 0.894 | |
Resistance | 18 (10.0) | 0.833 | |
No pathogen detected | 31 (17.1) | 0.903 | |
Shock within 48 h after ICU admission | 0.001 | ||
No | 95 (52.5) | 0.979 | |
Yes | 86 (47.5) | 0.791 | |
Leukocyte count, 109/L | 0.010 | ||
≤ 4 | 31 (17.1) | 0.774 | |
4 < WBC ≤ 12 | 77 (42.6) | 0.963 | |
> 12 | 73 (40.3) | 0.863 | |
Lymphocyte to neutrophil ratio | 0.035 | ||
≤ 0.15 | 148 (81.8) | 0.912 | |
> 0.15 | 33 (18.2) | 0.788 | |
International standardized ratio | 0.001 | ||
≤ 1.5 | 127 (70.2) | 0.937 | |
> 1.5 | 54 (29.8) | 0.778 | |
Activated partial thromboplastin time, s | 0.064 | ||
≤ 50 | 138 (76.2) | 0.913 | |
> 50 | 43 (23.8) | 0.814 | |
Albumin, g/L | 0.058 | ||
≤ 30 | 99 (54.7) | 0.848 | |
> 30 | 82 (45.3) | 0.939 | |
Creatinine, μmol/L | 0.001 | ||
≤ 120 | 150 (82.9) | 0.927 | |
> 120 | 31 (17.1) | 0.710 | |
Cardiac troponin I, ng/mL | 0.063 | ||
≤ 0.05 | 138 (76.2) | 0.913 | |
> 0.05 | 43 (23.8) | 0.814 | |
Procalcitonin, ng/mL | 0.011 | ||
≤ 5 | 93 (51.4) | 0.946 | |
> 5 | 88 (48.6) | 0.830 | |
Lactic acid, mmol/L | 0.001 | ||
≤3 | 128 (70.7) | 0.938 | |
> 3 | 53 (29.3) | 0.774 | |
Oxygenation index, mmHg | 0.003 | ||
≤ 200 | 97 (53.6) | 0.825 | |
> 200 | 84 (46.4) | 0.964 | |
SOFA score | 0.001 | ||
≤ 8 | 124 (68.5) | 0.968 | |
> 8 | 57 (31.5) | 0.719 |
Table 3 Multiple analysis of sepsis patients
Factor | RR | 95%CI | P value | |
Lower limit | Upper limit | |||
BMI (Ref) | 0.011 | |||
BMI (1) | 1.778 | 0.532 | 5.942 | 0.350 |
BMI (2) | 0.377 | 0.113 | 1.262 | 0.114 |
Lactic acid | 2.950 | 1.168 | 7.450 | 0.022 |
SOFA score | 8.359 | 2.741 | 25.496 | 0.001 |
- Citation: Chen RX, Wu ZQ, Li ZY, Wang HZ, Ji JF. Prognostic predictors in patients with sepsis after gastrointestinal tumor surgery: A retrospective study. World J Gastrointest Surg 2021; 13(3): 256-266
- URL: https://www.wjgnet.com/1948-9366/full/v13/i3/256.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v13.i3.256