Systematic review of anorectal leiomyosarcoma: Current challenges and recent advances

Table 1 Patient characteristics, n (%)

Characteristic	Data
Location, n = 51%
Rectal	47 (92.2)
Anal	4 (7.8)
Sex, n = 51%
Female	26 (51)
Male	25 (49)
Mean age ± standard deviation, n = 51	60 ± 17.1 yr
Median tumor size (IQR), n = 38	6 (1.5-22) cm
Mean mitotic rate ± standard deviation of mitoses/50 HPF, n = 21	68.1 ± 40.42
Grade, n = 16%
High	10 (62.5)
Intermediate	2 (12.5)
Low	4 (25)
Symptoms, n = 35%
Rectal bleeding	17 (48.57)
Pain, rectal/abdominal	13 (37.14)
Weight loss	4 (11.43)
Constipation	4 (11.43)
Altered bowel motion	3 (8.57)
Protruding mass	3 (8.57)
Asymptomatic	3 (8.57)
Surgery, n = 45%
Wide local excision	11 (24.4)
Abdominoperineal resection	14 (31.11)
Low anterior resection	12 (26.7)
Others	8 (17.8)
Outcome, n = 31%
DOD	13 (41.94)
ANED	11 (35.48)
AWD	4 (12.9)
DDD	3 (9.68)

ANED: Alive with no evidence of disease; AWD: Alive with the disease; DDD: Died of a different disease; DOD: Died of disease(LMS); HPF: High power field; IQR: Interquartile range.