Pancreatogastrostomy vs pancreatojejunostomy after pancreaticoduodenectomy: An updated meta-analysis of RCTs and our experience

Table 1 Characteristic of included trials

Author	Year	Country	Study type	Number of PG	Number of PJ	Definition of PF
Yeo et al[14]	1995	United States	Single blind, controlled randomized, single center trial	73	72	PF was defined as drainage of greater than 50 mL of amylase-rid fluid on or after postoperative day 10
Duffas et al[23]	2005	France	Single blind, controlled randomized, multicenter trial	81	68	Fluid obtained through drains or percutaneous aspiration, containing at least 4 times normal serum values of amylase for 3 day
Bassi et al[25]	2005	Italy	Single blind, controlled randomized, single center trial	69	82	Any clinically significant output of fluid, rich in amylase, confirmed by fistulography
Bassi et al[8]	2008	Spain	Single blind, controlled randomized, single center trial	53	55	ISGPF definition
Wellner et al[15]	2012	Germany	Single blind, controlled randomized, single center trial	59	57	ISGPF definition
Wang et al[30]	2012	China	Single blind, controlled randomized, multicenter trial	83	53	ISGPF definition
El Nakeeb et al[20]	2013	Egypt	Single blind, controlled randomized, single center trial	45	45	ISGPF definition
Topal et al[18]	2013	Belgium	Single blind, controlled randomized, multicenter trial	162	167	ISGPF definition
Figueras et al[22]	2013	Spain	Single blind, controlled randomized, multicenter trial	65	58	ISGPF definition
Grendar et al[24]	2015	Canada	Single blind, controlled randomized, single center trial	48	50	Either radiologically proven anastomotic leak or continued drainage (via drain, enterocutaneous fistula, or wound) of lipase­rich fluid on postoperative day 10
Keck et al[19]	2016	Germany	Single blind, controlled randomized, multicenter trial	171	149	ISGPF definition

PG: Pancreaticogastrostomy; PJ: Pancreaticojejunostomy; PF: Postoperative pancreatic fistula.