Nutritional status and adjuvant chemotherapy in gastric cancer: An underestimated determinant of treatment success

doi:10.4240/wjgs.v18.i5.118610

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. May 27, 2026; 18(5): 118610
Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.118610

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Figure 1 Nutritional impairment as a driver of reduced chemotherapy dose intensity in gastric cancer. The figure conceptualizes the biological and clinical cascade linking malnutrition to impaired delivery of adjuvant chemotherapy. Host-related factors, including sarcopenia and systemic inflammation, promote increased toxicity and decreased treatment tolerance, ultimately leading to suboptimal dose intensity and inferior survival outcomes. This framework supports a shift toward patient-centered, nutrition-integrated oncologic care. RDI: Relative dose intensity.

Citation: Schiano di Visconte M, Sarnari S, Brillantino A, Marano L, Talento P, Guttadauro A. Nutritional status and adjuvant chemotherapy in gastric cancer: An underestimated determinant of treatment success. World J Gastrointest Surg 2026; 18(5): 118610
URL: https://www.wjgnet.com/1948-9366/full/v18/i5/118610.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i5.118610

Schiano di Visconte M, Sarnari S, Brillantino A, Marano L, Talento P, Guttadauro A. Nutritional status and adjuvant chemotherapy in gastric cancer: An underestimated determinant of treatment success. World J Gastrointest Surg 2026; 18(5): 118610 [DOI: 10.4240/wjgs.v18.i5.118610]

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